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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Serine/threonine kinase 25

STK25, SOK1, Ste20-like kinase SLK, YSK1
Top mentioned proteins: PAK1, CAN, Src, V1a, ACID
Papers using STK25 antibodies
YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3ζ
Supplier
Barr Francis A. et al., In The Journal of Cell Biology, 2002
... Peptide antibodies to YSK1 (SC-6865, N19) and MST4 (3822) were purchased from Santa Cruz Biotechnology, Inc ...
Papers on STK25
Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in humans.
New
Mahlapuu et al., Göteborg, Sweden. In Diabetologia, Feb 2016
We recently identified serine/threonine protein kinase 25 (STK25) as a regulator of liver steatosis, whole-body glucose tolerance and insulin sensitivity in a mouse model system.
A novel 2q37 microdeletion containing human neural progenitors genes including STK25 results in severe developmental delay, epilepsy, and microcephaly.
New
Carvalho et al., Boston, United States. In Am J Med Genet A, Nov 2015
The deleted segment contains genes that are highly expressed in the developing human cortical plate and the subventricular zone (SVZ) in vivo and human neural progenitors in vitro, including SEPT2, THAP4, ATG4B, PPP1R7, and STK25.
MST kinases in development and disease.
Review
New
Sahai et al., London, United Kingdom. In J Cell Biol, Oct 2015
The mammalian MST kinase family, which is related to the Hippo kinase in Drosophila melanogaster, includes five related proteins: MST1 (also called STK4), MST2 (also called STK3), MST3 (also called STK24), MST4, and YSK1 (also called STK25 or SOK1).
Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model.
New
Mahlapuu et al., Göteborg, Sweden. In Diabetes, Aug 2015
We recently identified serine/threonine protein kinase 25 (STK25) as a negative regulator of glucose and insulin homeostasis based on observations in myoblasts with acute depletion of STK25 and in STK25-overexpressing transgenic mice.
Recruitment and activation of SLK at the leading edge of migrating cells requires Src family kinase activity and the LIM-only protein 4.
New
Sabourin et al., Ottawa, Canada. In Biochim Biophys Acta, Jul 2015
The Ste20-like kinase SLK plays a pivotal role in cell migration and focal adhesion turnover and is regulated by the LIM domain-binding proteins Ldb1 and Ldb2.
Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH.
New
Mahlapuu et al., Göteborg, Sweden. In Faseb J, Apr 2015
We recently identified serine/threonine protein kinase 25 (STK25) as a regulator of whole-body insulin and glucose homeostasis.
Germinal Center Kinases SmKIN3 and SmKIN24 Are Associated with the Sordaria macrospora Striatin-Interacting Phosphatase and Kinase (STRIPAK) Complex.
Pöggeler et al., Göttingen, Germany. In Plos One, 2014
Using the mammalian germinal center kinases (GCKs) MST4, STK24, STK25 and MINK1 as query, we identified the two putative homologs SmKIN3 and SmKIN24 in S. macrospora.
Biosynthesis of colabomycin E, a new manumycin-family metabolite, involves an unusual chain-length factor.
Petříček et al., Praha, Czech Republic. In Chembiochem, 2014
Colabomycin E is a new member of the manumycin-type metabolites produced by the strain Streptomyces aureus SOK1/5-04 and identified by genetic screening from a library of streptomycete strains.
Structural insights into regulatory mechanisms of MO25-mediated kinase activation.
Zhou et al., Shanghai, China. In J Struct Biol, 2014
The adaptor molecule MO25 not only recruits and activates LKB1 through the pseudokinase STRAD, but also may directly activate GCKs like MST3, MST4, STK25, OSR1 and SPAK.
Essential role for the SLK protein kinase in embryogenesis and placental tissue development.
Sabourin et al., In Dev Dyn, 2014
BACKGROUND: Over the past decade, the Ste20-like kinase SLK, has been implicated in several signaling processes.
Differential expression of MST4, STK25 and PDCD10 between benign prostatic hyperplasia and prostate cancer.
Zhao et al., Beijing, China. In Int J Clin Exp Pathol, 2013
Both serine/threonine protein kinase MST4 (MST4) and serine/threonine kinase 25 (STK25) belong to the Ste20-like kinases and interact with programmed cell death 10 (PDCD10) which is closely linked to cancer diseases.
SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein-protein interactions.
Review
Clerk et al., Reading, United Kingdom. In Biochem J, 2013
The GCKIII (germinal centre kinase III) subfamily of the mammalian Ste20 (sterile 20)-like group of serine/threonine protein kinases comprises SOK1 (Ste20-like/oxidant-stress-response kinase 1), MST3 (mammalian Ste20-like kinase 3) and MST4.
Ste20-like kinase SLK, at the crossroads: a matter of life and death.
Review
Sabourin et al., Ottawa, Canada. In Cell Adh Migr, 2013
Over the last several years, we and others have established distinct roles for the Ste20-like kinase SLK, encompassing apoptosis, growth, motility and development.
STK25 protein mediates TrkA and CCM2 protein-dependent death in pediatric tumor cells of neural origin.
GeneRIF
Fainzilber et al., Israel. In J Biol Chem, 2012
Down-modulation of STK25, but not STK24, rescued medulloblastoma cells from NGF-induced TrkA-dependent cell death, suggesting that STK25 is part of the death-signaling pathway initiated by TrkA and CCM2.
Serine/threonine protein kinase 25 (STK25): a novel negative regulator of lipid and glucose metabolism in rodent and human skeletal muscle.
GeneRIF
Mahlapuu et al., Göteborg, Sweden. In Diabetologia, 2012
Significantly higher STK25 levels were observed in the skeletal muscle of type 2 diabetic patients, compared with individuals with normal glucose tolerance.
Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice.
GeneRIF
Howell et al., Syracuse, United States. In Plos One, 2011
Stk25 is a genetic modifier of Tau phosphorylation in Dab1-mutant mice.
PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress.
GeneRIF
Ma et al., Beijing, China. In Front Biosci, 2011
PDCD10 might be a regulatory adaptor required for STK25 functions, which differ distinctly depending on the redox status of the cells that may be potentially related to tumor progression.
Downregulation of SOK1 promotes the migration of MCF-7 cells.
GeneRIF
Cho et al., Shanghai, China. In Biochem Biophys Res Commun, 2011
The results of the study results indicate that attenuation of SOK1 enhanced cell migration and lead to changes in the expression of migration-associated proteins such as FAK and GM130.
Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment.
Impact
GeneRIF
Howell et al., Syracuse, United States. In Cell, 2010
This demonstrates that the balance between Reelin-Dab1 signaling and LKB1-Stk25-GM130 regulates Golgi dispersion, axon specification, and dendrite growth and provides insights into the importance of the Golgi apparatus for cell polarization.
A novel role for the Ste20 kinase SLK in adhesion signaling and cell migration.
Review
Sabourin et al., Ottawa, Canada. In Cell Adh Migr, 2009
Recently, we have shown that, in addition to cell death, the Ste20-like kinase SLK is required for efficient cell migration in fibroblasts.
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