Producing GM-CSF: a unique T helper subset?
New Haven, United States. In Cell Res, 21 Dec 2014
An article by Sheng et al. recently published by Cell Research now suggests that the differentiation program of GM-CSF-producing cells from naïve CD4 T cells is distinct from that of Th1 and Th17 cells, and is regulated by the IL-7-STAT5 axis.
GENETIC CHARACTERISATION OF A COHORT OF CHILDREN CLINICALLY LABELLED AS GROWTH HORMONE OR IGF-1 INSENSITIVITY: DIAGNOSTIC VALUE OF SERUM IGF-1 AND HEIGHT AT PRESENTATION.
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London, United Kingdom. In Eur J Endocrinol, 19 Dec 2014
Methods: As a genetics referral centre, we have sequenced appropriate candidate genes (GHR, the GHR pseudoexon (6Ψ), STAT5B, IGFALS, IGF1, IGF1R, OBSL1, CUL7 and CCDC8) in subjects referred with suspected GHI (n=69) or IGF-1 insensitivity (n=3).