Polymorphisms in JAK/STAT signaling pathway genes and risk of non-Hodgkin lymphoma.
Beijing, China. In Leuk Res, 11 Jul 2013
We evaluated the association between genetic polymorphisms (SNPs) in 12 JAK/STAT pathway genes (JAK3, STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, STAT6, SCOS1, SCOS2, SCOS3, and SCOS4) and NHL risk in a population-based case-control study of Connecticut women.
Growth hormone and cell growth.
Australia. In Endocr Dev, 2011
GH acts via its cell membrane receptor to initiate a range of signalling pathways, with JAK2 kinase activation of STAT5 being the most important.
Spectrum of insulin-like growth factor deficiency.
More papers using
Leiden, Netherlands. In Endocr Dev, 2011
Of the three GH signal transduction defects, a STAT5B defect is well established, but abnormalities in the MAPK pathway (such as PTPN11 mutations in Noonan syndrome) and NF-ĸB pathway (IĸBα mutation) may also cause IGFD.