Mutant prolactin receptor and familial hyperprolactinemia.
Glasgow, United Kingdom. In N Engl J Med, Dec 2013
This substitution disrupted the high-affinity ligand-binding interface of the prolactin receptor, resulting in a loss of downstream signaling by Janus kinase 2 (JAK2) and signal transducer and activator of transcription 5 (STAT5).
STAT5 in hematopoietic stem cell biology and transplantation.
Atlanta, United States. In Jakstat, Nov 2013
UNLABELLED: Signal transducer and activator of transcription 5 (STAT5) regulates normal lympho-myeloid development through activation downstream of early-acting cytokines, their receptors, and Janus kinases (JAKs).
STATs get their move on.
More papers using
Stony Brook, United States. In Jakstat, Nov 2013
Distinctly, STAT3, STAT5, and STAT6 are continually imported to the nucleus independent of tyrosine phosphorylation.