Recycled IL-7 Can Be Delivered to Neighboring T Cells.
Cleveland, United States. In J Immunol, 13 May 2015
In this article, we provide evidence that IL-7 utilization is enhanced by a novel mechanism of cytokine "recycling" during which T cells treated with rIL-7 are rapidly induced to express p-STAT5 and are subsequently able to recycle biologically active cytokine for release to neighboring cells in soluble form.
Prolactin-induced prostate tumorigenesis.
Paris, France. In Adv Exp Med Biol, Dec 2014
Mainly through the activation of its downstream target STAT5, PRL can induce growth and survival of prostate cancer cells and tissues in several experimental settings.
Prolactin-induced protein in breast cancer.
More papers using
Iowa City, United States. In Adv Exp Med Biol, Dec 2014
Expression of PIP in breast cancer is regulated by androgen and prolactin through a number of transcription factors and signaling cross-talks, including STAT5, Runx2, and CREB1.