Producing GM-CSF: a unique T helper subset?
New Haven, United States. In Cell Res, 21 Dec 2014
An article by Sheng et al. recently published by Cell Research now suggests that the differentiation program of GM-CSF-producing cells from naïve CD4 T cells is distinct from that of Th1 and Th17 cells, and is regulated by the IL-7-STAT5 axis.
Mechanisms of Resistance to Cabazitaxel.
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Stanford, United States. In Mol Cancer Ther, 21 Dec 2014
Among multidrug resistant (MDR) variants, cabazitaxel was relatively less cross-resistant than paclitaxel and docetaxel (15 vs. 200-fold in MES-SA/Dx5 and 9 vs. 60-fold in MCF-7/TxT50, respectively).