High-resolution antibody array analysis of childhood acute leukemia cells.
Praha, Czech Republic. In Mol Cell Proteomics, 19 Feb 2016
From non-CD markers, we found DBN1, PAX5, or PTK2 overexpressed in B-cell precursor acute lymphoblastic leukemias, LAT, SH2D1A, or STAT5A overexpressed in T-cell acute lymphoblastic leukemias, and HCK, GLUD1, or SYK overexpressed in acute myeloid leukemias.
Reductive silylation of Cp*UO2((Mes)PDI(Me)) promoted by Lewis bases.
West Lafayette, United States. In Dalton Trans, 18 Feb 2016
UNASSIGNED: Functionalization of the uranyl moiety (UO2(2+)) in Cp*UO2((Mes)PDI(Me)) () ((Mes)PDI(Me) = 2,6-((Mes)N[double bond, length as m-dash]CMe)2C5H3N; Mes = 2,4,6-triphenylmethyl), which bears a reduced, monoanionic pyridine(diimine) ligand, is reported.
Immune homeostasis enforced by co-localized effector and regulatory T cells.
Bethesda, United States. In Nature, 10 Jan 2016
Here we use multiplex, quantitative imaging in mice to show that, within secondary lymphoid tissues, highly suppressive Treg cells expressing phosphorylated STAT5 exist in discrete clusters with rare IL-2-positive T cells that are activated by self-antigens.
Hesperidin Inhibits Vascular Formation by Blocking the AKT/mTOR Signaling Pathways.
South Korea. In Prev Nutr Food Sci, 31 Dec 2015
In the present study, we evaluated whether hesperidin has anti-angiogenic effects in mouse embryonic stem cell (mES)-derived endothelial-like cells, and human umbilical vascular endothelial cells (HUVECs), and evaluated their mechanism via the AKT/mammalian target of rapamycin (mTOR) signaling pathway.
Analysis of differentially expressed genes based on microarray data of glioma.
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Nanjing, China. In Int J Clin Exp Med, 2014
In addition, the transcription factor analysis showed these DEGs were regulated by the binding sites of transcription factors GLI2, SP1, SMAD7, SMAD3, RELA, STAT5B, CTNNB1, STAT5A, TFAP2A and SP3.