EGFR and EGFRvIII in Glioblastoma: Partners in Crime.
Toronto, Canada. In Cancer Cell, 14 Nov 2013
In this issue of Cancer Cell, Weiss and colleagues implicate phosphorylation of EGFRvIII by EGFR and the consequent phosphorylation of STAT3 as a signaling axis that drives transformation in glioblastoma.
JAK-STAT and bone metabolism.
Indianapolis, United States. In Jakstat, Aug 2013
Furthermore, STAT3 has more profound effects on bone homeostasis compared with the other STATs.
Mechanisms of chronic JAK-STAT3-SOCS3 signaling in obesity.
Köln, Germany. In Jakstat, May 2013
UNLABELLED: Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling pathways are critical for the maintenance of homeostatic and developmental processes; however, deregulation and chronic activation of JAK-STAT3 results in numerous diseases.
Role of STAT3 in Cancer Metastasis and Translational Advances.
More papers using
Mumbai, India. In Biomed Res Int, Dec 2012
UNLABELLED: Signal transducer and activator of transcription 3 (STAT3) is a latent cytoplasmic transcription factor, originally discovered as a transducer of signal from cell surface receptors to the nucleus.
Assessing implicit models for nonpolar mean solvation forces: the importance of dispersion and volume terms.
In PLoS ONE, 2005
... 14-3-3σ, 14-3-3θ, 14-3-3β, GAPDH antibodies (Santa Cruz Biotechnology, Santa Cruz, CA), 14-3-3γ, 14-3-3η, Stat3, pY705-Stat3, pS727-Stat3 antibodies (Cell Signaling, Danvers, MA), HA tag, ... Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs.
In PLoS Biology, 2004
... Antibodies for the following targets were used: STAT1 (BD Biosciences Franklin Lakes, NJ, USA), STAT3 (Santa Cruz Biotech, Santa Cruz, CA, USA), HA (Cell Signaling Technology, Beverly, MA, USA), ... Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis.
In PLoS ONE, 2003
... phospho (p)-EGFR (Y1068, Y1045), Bcl-xL, Mcl-1, Bid, p-Bad (S112), Bad, PI3K, ERK, p-ERK (T202/Y204), STAT3, p-STAT3 (Y705), aldolase, and H3 (Cell Signaling, Danvers, MA, USA) ...