GUGGULSTERONE FOR CHEMOPREVENTION OF CANCER.
Houston, United States. In Curr Pharm Des, 12 Dec 2015
Guggulsterone mediates gene expression through the modulation of several transcription factors, including NF-B, STAT3, C/EBP, androgen receptor, and glucocorticoid receptors.
Erythropoietin Stimulates Tumor Growth via EphB4.
Houston, United States. In Cancer Cell, 09 Dec 2015
Here, we identified EphB4 as an Epo receptor that triggers downstream signaling via STAT3 and promotes rhEpo-induced tumor growth and progression.
Molecular mechanisms underlying anticancer effects of myricetin.
Kāraikkudi, India. In Life Sci, 06 Nov 2015
Most importantly, myricetin interacts with oncoproteins such as protein kinase B (PKB) (Akt), Fyn, MEK1, and JAK1- STAT3 (Janus kinase-signal transducer and activator of transcription 3), and it attenuates the neoplastic transformation of cancer cells.
STATs: An Old Story, Yet Mesmerizing.
Tehrān, Iran. In Cell J, Dec 2014
In this review we explain Janus kinase (JAK)/STAT signaling and focus on STAT3, which is transient from cytoplasm to nucleus after phosphorylation.
Role of STAT3 in lung cancer.
More papers using
San Diego, United States. In Jakstat, 2013
Accumulating evidence over the last 2 decades suggests a critical role for Signal Transducer and Activator of Transcription 3 (STAT3) as a point of convergence for various signaling pathways that are dysregulated in the disease.
Assessing implicit models for nonpolar mean solvation forces: the importance of dispersion and volume terms.
In PLoS ONE, 2005
... 14-3-3σ, 14-3-3θ, 14-3-3β, GAPDH antibodies (Santa Cruz Biotechnology, Santa Cruz, CA), 14-3-3γ, 14-3-3η, Stat3, pY705-Stat3, pS727-Stat3 antibodies (Cell Signaling, Danvers, MA), HA tag, ... Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs.
In PLoS Biology, 2004
... Antibodies for the following targets were used: STAT1 (BD Biosciences Franklin Lakes, NJ, USA), STAT3 (Santa Cruz Biotech, Santa Cruz, CA, USA), HA (Cell Signaling Technology, Beverly, MA, USA), ... Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis.
In PLoS ONE, 2003
... phospho (p)-EGFR (Y1068, Y1045), Bcl-xL, Mcl-1, Bid, p-Bad (S112), Bad, PI3K, ERK, p-ERK (T202/Y204), STAT3, p-STAT3 (Y705), aldolase, and H3 (Cell Signaling, Danvers, MA, USA) ...