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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

ST3Gal I
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008] (from NCBI)
Papers using ST3Gal I antibodies
Delineation of the minimal catalytic domain of human Galbeta1-3GalNAc alpha2, 3-sialyltransferase (hST3Gal I)
Supplier
Burchell Joy et al., In Glycobiology, 2000
... A 2.5-kb Sal I-Sca I fragment containing the MUC1 promoter fused to ST3Gal-I was purified (Qiagen kit) and dissolved in ...
Papers on ST3Gal I
Over-expression of ST3Gal-I promotes mammary tumorigenesis.
GeneRIF
Burchell et al., Canada. In Glycobiology, 2010
Over-expression of ST3Gal-I promotes mammary tumorigenesis.
Mutational analysis for enzyme activity of mouse Galbeta1,3GalNAc alpha2,3-sialyltransferase (mST3Gal I).
GeneRIF
Lee et al., Pusan, South Korea. In Indian J Biochem Biophys, 2010
tryptophan and cysteine residues conserved in ST3Gal I are critical for its activity
ST3Gal.I sialyltransferase relevance in bladder cancer tissues and cell lines.
GeneRIF
Dall'Olio et al., Lisbon, Portugal. In Bmc Cancer, 2008
ST3Gal.I plays the major role in the sialylation of the T antigen in bladder cancer.
Family-based association study of lithium-related and other candidate genes in bipolar disorder.
GeneRIF
Sklar et al., Boston, United States. In Arch Gen Psychiatry, 2008
evidence of the association of bipolar disorder with SIAT4A was seen
Sialyl-Lewis(x) on P-selectin glycoprotein ligand-1 is regulated during differentiation and maturation of dendritic cells: a mechanism involving the glycosyltransferases C2GnT1 and ST3Gal I.
GeneRIF
Burchell et al., London, United Kingdom. In J Immunol, 2007
regulation of O-glycosylation controls sLe(x) expression, and also suggest that O-glycans may have a function in dendritic cells migration
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