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Synovial sarcoma, X breakpoint 2 interacting protein

SSX2IP, A dip, SSX2 interacting protein, afadin DIL domain-interacting protein
This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Oct 2009] (from NCBI)
Top mentioned proteins: CAN, SIMPLE, HAD, V1a, STEP
Papers on SSX2IP
WDR8 is a centriolar satellite and centriole-associate protein that promotes ciliary vesicle docking during ciliogenesis.
New
Pereira et al., Heidelberg, Germany. In J Cell Sci, Jan 2016
We show that WDR8 interacts with the satellite proteins SSX2IP and PCM1 as well as the centriolar proximal end component Cep135.
The conserved Wdr8-hMsd1/SSX2IP complex localises to the centrosome and ensures proper spindle length and orientation.
New
Toda et al., London, United Kingdom. In Biochem Biophys Res Commun, Jan 2016
Furthermore, we identified hMsd1/SSX2IP, a conserved spindle anchoring protein, as one of Wdr8 interactors by mass spectrometry.
Centriolar satellite- and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assembly.
New
Toda et al., London, United Kingdom. In Mol Biol Cell, Jul 2015
hMsd1/SSX2IP localizes to both the centrosome and centriolar satellites and is required for tethering microtubules to the centrosome.
The Msd1-Wdr8-Pkl1 complex anchors microtubule minus ends to fission yeast spindle pole bodies.
New
Toda et al., Hiroshima, Japan. In J Cell Biol, Jun 2015
The conserved Msd1/SSX2IP proteins are localized to the spindle pole body (SPB) and the centrosome in fission yeast and humans, respectively, and play a critical role in microtubule anchoring.
Spectroscopic and viscometric elucidation of the interaction between a potential chloride channel blocker and calf-thymus DNA: the effect of medium ionic strength on the binding mode.
New
Guchhait et al., Calcutta, India. In Phys Chem Chem Phys, Feb 2015
A dip-and-rise characteristic of the rotational relaxation profile of the drug within the DNA environment has been argued to be originating from a substantial difference in the lifetime as well as amplitude of the free and DNA bound drug molecule.
Exploring causal networks underlying fat deposition and muscularity in pigs through the integration of phenotypic, genotypic and transcriptomic data.
Rosa et al., Madison, United States. In Bmc Syst Biol, 2014
One genomic region on SSC6 showed significant associations with three relevant phenotypes, off-midline10th-rib backfat thickness, loin muscle weight, and average intramuscular fat percentage, and also with the expression of seven genes, including ZNF24, SSX2IP, and AKR7A2.
A dip-stick type biosensor using bioluminescent bacteria encapsulated in color-coded alginate microbeads for detection of water toxicity.
Gu et al., Seoul, South Korea. In Analyst, 2014
The use of genetically engineered bioluminescent bacteria, in which bioluminescence is induced by different modes of toxic action, represents an alternative to acute toxicity tests using living aquatic organisms (plants, vertebrates, or invertebrates) in an aqueous environment.
Microsatellite genome-wide association study for mandibular prognathism.
Iida et al., Japan. In Am J Orthod Dentofacial Orthop, 2014
RESULTS: Two suggestive associations on chromosomes 1q32.2 (D1S1358i: P = 4.22 × 10(-4)) and 1p22.3 (D1S0411i: P = 6.66 × 10(-4)) were shown, and PLXNA2 and SSX2IP were suggested to be candidate genes; 1p22.3 flanked the region indicated by previous linkage analysis.
Interaction of a potential chloride channel blocker with a model transport protein: a spectroscopic and molecular docking investigation.
Guchhait et al., Calcutta, India. In Phys Chem Chem Phys, 2014
A dip-and-rise characteristic of the rotational relaxation profile of the drug within the protein has been argued to originate from a significant difference in the lifetime as well as amplitude of the free and protein-bound drug molecule.
[Clinical application of the tidal flow-volume curve--a computer simulation].
Ohtsuka, In Masui, 2014
A dip in the expiratory tidal V-V curve was observed with a peripheral airway obstruction model.
Dip biosensor based on localized surface plasmon resonance at the tip of an optical fiber.
Monro et al., Adelaide, Australia. In Langmuir, 2014
A dip biosensor is realized by depositing metallic nanoparticles onto the tip of a cleaved optical fiber.
The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone.
Gruss et al., Heidelberg, Germany. In Mol Biol Cell, 2014
Here we characterize the function of a novel centriolar satellite protein, synovial sarcoma X breakpoint-interacting protein 2 (SSX2IP), in the assembly of primary cilia.
Msd1/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation.
Toda et al., London, United Kingdom. In Embo Rep, 2014
Here we show that the conserved human Msd1/SSX2IP is required for microtubule anchoring.
Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 protein.
GeneRIF
Ogita et al., Kōbe, Japan. In J Biol Chem, 2012
The results indicate that ADIP plays an essential role in PDGF-induced cell movement by interacting with afadin and Vav2 and regulating the activation of Rac.
SSX2IP expression in acute myeloid leukaemia: an association with mitotic spindle failure in t(8;21), and cell cycle in t(15;17) patients.
GeneRIF
Greiner et al., In Br J Haematol, 2008
data shows that SSX2IP is affected in two ways that relate to the cell cycling of acute myeloid leukaemia cells
SSX2IP: an emerging role in cancer.
Review
Guinn et al., London, United Kingdom. In Biochem Biophys Res Commun, 2007
We describe the emerging role of Synovial Sarcoma X breakpoint 2 Interacting Protein (SSX2IP) in cancer and its still largely unknown function in human cells.
Secondary extinction and diffraction behaviors in cylindrical crystals.
Impact
Hu, Beijing, China. In Acta Crystallogr A, 2003
A dip was found in the curve of the extinction factor y( micro ) against tau(0) for given theta(B) and xi(0), and the position of this minimum shifts toward smaller tau(0) with increasing xi(0) or theta(B).
ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions.
GeneRIF
Takai et al., Suita, Japan. In J Biol Chem, 2003
localization at cell-cell adherens junctions
The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.
GeneRIF
van Kessel et al., Nijmegen, Netherlands. In Genes Chromosomes Cancer, 2002
Nuclear protein SS2IP interacts with cancer-related protein SSX2 and the human homologue of a Ras-like GTPase interactor, RABIN3.
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