Making the diagnosis of Sjögren's syndrome in patients with dry eye.
Westerville, United States. In Clin Ophthalmol, Dec 2015
Examination of classic SS biomarkers (SS-A/Ro, SS-B/La, antinuclear antibody, and rheumatoid factor) is a convenient and non-invasive way of evaluating patients for the presence of SS, even years prior to confirmed diagnosis, although not all SS patients will test positive, particularly those with early disease.
Functional roles of non-coding Y RNAs.
Cambridge, United Kingdom. In Int J Biochem Cell Biol, Sep 2015
Y RNAs are essential for the initiation of chromosomal DNA replication in vertebrates and, when bound to the Ro60 protein, they are involved in RNA stability and cellular responses to stress in several eukaryotic and prokaryotic species.
Los Angeles, United States. In Lancet, 2005
A new international consensus for diagnosis requires objective signs and symptoms of dryness including a characteristic appearance of a biopsy sample from a minor salivary gland or autoantibody such as anti-SS-A.