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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

SRSF protein kinase 3

This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] (from NCBI)
Top mentioned proteins: MMP-3, HAD, STC, Presenilin-1, CIs
Papers on SRPK3
Alternative splicing of MEF2C pre-mRNA controls its activity in normal myogenesis and promotes tumorigenicity in rhabdomyosarcoma cells.
Davie et al., Carbondale, United States. In J Biol Chem, Feb 2015
We also identified a serine protein kinase, SRPK3, that was down-regulated in RMS cells and found that expression of SRPK3 promoted the splicing of the MEF2Cα2 isoform and induced differentiation.
Contiguous ABCD1 DXS1357E deletion syndrome: report of an autopsy case.
Shimozawa et al., Tochigi, Japan. In Neuropathology, 2013
Array comparative genomic hybridization (CGH) analysis suggested that the deletion was a genomic rearrangement in the 90-kb span starting in DXS1357E/BACP31 exon 4 and included ABCD1, PLXNB3, SRPK3, IDH3G and SSR4, ending in PDZD4 exon 8. Thus, the absence of ALDP, when combined with defects in the B-cell antigen receptor associated protein 31 (BAP31) and other factors, severely affects VLCFA metabolism on peroxisomal functions and produces ZS-like pathology.
Novel role of NADPH oxidase in ischemic myocardium: a study with Nox2 knockout mice.
Maulik et al., Farmington, United States. In Funct Integr Genomics, 2012
Selected differentially regulated genes such as β-catenin, SRPK3, ERDR1, ACIN1, Syntaxin-8, and STC1 were validated by real-time PCR.
Molecular characterization and expression patterns of serine/arginine-rich specific kinase 3 (SPRK3) in porcine skeletal muscle.
Feng et al., Wuhan, China. In Mol Biol Rep, 2011
SRPK3 is a protein kinase belonging to serine/arginine protein kinases (SRPK) family, which phosphorylates serine/arginine repeat-containing proteins, and is controlled by a muscle-specific enhancer directly regulated by MEF2.
Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2.
Olson et al., Dallas, United States. In Genes Dev, 2005
normal muscle growth and homeostasis require MEF2-dependent signaling by Srpk3
Large-scale methylation analysis of human genomic DNA reveals tissue-specific differences between the methylation profiles of genes and pseudogenes.
Rosenthal et al., Jena, Germany. In Hum Mol Genet, 2000
Two of the genes, SLC6A8 and MSSK1, are tissue-specifically expressed.
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