The role of tissue factor isoforms in cancer biology.
Berlin, Germany. In Int J Cancer, Sep 2015
The TF isoform expression is differentially modulated on post-transcriptional level via regulatory factors, such as serine/arginine-rich (SR) proteins, SR protein kinases and micro (mi)RNAs.
Alternative splicing regulation impacts heart development.
Houston, United States. In Cell, 2005
In this issue of Cell, Xu et al. (2005) demonstrate that a heart-specific knockout of one SR protein, ASF/SF2, produces cardiomyopathy and misregulation of specific alternative splicing events during early postnatal development.