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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Spi-C transcription factor

spiC
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Top mentioned proteins: HAD, CAN, PU.1, Spi-B, V1a
Papers on spiC
Preparation of Monoclonal Antibodies Against SpiC Protein Secreted by T3SS-2 of Salmonella spp.
New
Jiao et al., Yangzhou, China. In Monoclon Antib Immunodiagn Immunother, Dec 2015
SpiC protein, a member of Salmonella spp.
Prevalence of Antimicrobial Resistant and Virulent Salmonella spp. in Treated Effluent and Receiving Aquatic Milieu of Wastewater Treatment Plants in Durban, South Africa.
New
Olaniran et al., Durban, South Africa. In Int J Environ Res Public Health, Aug 2015
isolates recovered from the treated effluent and receiving surface waters, 93% harbored the spiC gene, 84% harbored the misL gene, and 87.5% harbored the orfL gene while 87% harbored the pipD gene.
Feverlike Temperature is a Virulence Regulatory Cue Controlling the Motility and Host Cell Entry of Typhoidal Salmonella.
New
Gal-Mor et al., Tel Aviv-Yafo, Israel. In J Infect Dis, Aug 2015
In contrast, we demonstrate up-regulation of particular Salmonella pathogenicity island 2 genes (especially spiC) and increased intraepithelial growth in a T3SS-2-dependent manner.
Identification of a negative regulatory role for spi-C in the murine B cell lineage.
New
DeKoter et al., London, Canada. In J Immunol, May 2015
To determine whether Spi-C functions as a negative regulator of Spi-B (encoded by Spib), mice were generated that were germline knockout for Spib and heterozygous for Spic (Spib(-/-)Spic(+/-)). Interestingly, loss of one Spic allele substantially rescued B cell frequencies and absolute numbers in Spib(-/-) mouse spleens.
Functions and development of red pulp macrophages.
Review
New
Tamura et al., Yokohama, Japan. In Microbiol Immunol, Feb 2015
Furthermore, the cell-intrinsic and -extrinsic factors (namely, Spi-C, IRF8/4, heme oxygenase-1, and M-CSF) that regulate the development and survival of RPMs have been identified.
[Prokaryotic expression and application of SpiC protein of Salmonella pullorum].
New
Xue et al., Yangzhou, China. In Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, Feb 2015
OBJECTIVE: To express the SpiC protein of Salmonella pullorum and establish an indirect ELISA method with SpiC protein as antigen.
The inverse agonist DG172 triggers a PPARβ/δ-independent myeloid lineage shift and promotes GM-CSF/IL-4-induced dendritic cell differentiation.
New
Müller et al., Marburg an der Lahn, Germany. In Mol Pharmacol, Feb 2015
DG172 also inhibited the expression of transcription factors driving granulocytic differentiation (Cebpe, Gfi1, and Klf5), and increased the levels of transcription factors promoting macrophage/DC differentiation (Irf4, Irf8, Spib, and Spic).
Immune reaction and survivability of salmonella typhimurium and salmonella infantis after infection of primary avian macrophages.
Berndt et al., Jena, Germany. In Plos One, 2014
Despite these host cell attacks, S. Typhimurium was better able than S. Infantis to survive within the macrophages and transcribed higher rates of the SPI-2 genes spiC, ssaV, sifA, and sseA.
Trichostatin A specifically improves the aberrant expression of transcription factor genes in embryos produced by somatic cell nuclear transfer.
Ogura et al., Tsukuba, Japan. In Sci Rep, 2014
Indeed, introduction of one of such transcription factors, Spi-C, into the embryos at least partially mimicked the TSA-induced improvement in embryonic development by activating gene networks associated with transcriptional regulation.
A microfluidic-based genetic screen to identify microbial virulence factors that inhibit dendritic cell migration.
Monack et al., Oakland, United States. In Integr Biol (camb), 2014
Our screen identified 7 Salmonella effectors (SseF, SifA, SspH2, SlrP, PipB2, SpiC and SseI) that inhibit DC chemotaxis toward CCL19.
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.
Impact
Murphy et al., Saint Louis, United States. In Cell, 2014
The transcription factor SPI-C is selectively expressed by RPM and is required for their development, but the physiologic stimulus inducing Spic is unknown.
SPIC: a novel similarity metric for comparing transcription factor binding site motifs based on information contents.
Su et al., In Bmc Syst Biol, 2012
METHODS: A novel metric has been proposed in this paper with name as SPIC (Similarity with Position Information Contents) for measuring the similarity between a column of a motif and a column of another motif.
Gene expression profiling of histiocytic sarcomas in a canine model: the predisposed flatcoated retriever dog.
Rutteman et al., Utrecht, Netherlands. In Plos One, 2012
RESULTS: QPCR analyses identified the significantly altered expression of nine genes; PPBP, SpiC, VCAM1, ENPEP, ITGAD (down-regulated), and GTSF1, Col3a1, CD90 and LUM (up-regulated) in the comparison of both the soft tissue and the visceral form with healthy spleen.
Regulation of follicular B cell differentiation by the related E26 transformation-specific transcription factors PU.1, Spi-B, and Spi-C.
GeneRIF
Garrett-Sinha et al., London, Canada. In J Immunol, 2011
Regulation of follicular B cell differentiation by the related E26 transformation-specific transcription factors PU.1, Spi-B, and Spi-C.
PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.
Impact
Bradley et al., Cambridge, United Kingdom. In Science, 2010
The PiggyBac screen uncovered many cancer genes not identified in previous retroviral or Sleeping Beauty transposon screens, including Spic, which encodes a PU.1-related transcription factor, and Hdac7, a histone deacetylase gene.
Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis.
Impact
GeneRIF
Murphy et al., Saint Louis, United States. In Nature, 2009
Spi-C controls development of red pulp macrophages required for red blood cell recycling and iron homeostasis
Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling.
GeneRIF
DeKoter et al., Cincinnati, United States. In Eur J Immunol, 2008
data indicate that ectopic expression of Spi-C can impair B-cell development and function by affecting genes associated with BCR signaling
Spi-C has opposing effects to PU.1 on gene expression in progenitor B cells.
GeneRIF
DeKoter et al., Cincinnati, United States. In J Immunol, 2006
Spi-C has the potential to modulate PU.1 activity to promote B cell differentiation.
SPI-C and STAT6 can cooperate to stimulate IgE germline transcription.
GeneRIF
Leanderson et al., Lund, Sweden. In Biochem Biophys Res Commun, 2006
A protein interaction between SPI-C and STAT6 is the basis for a novel mechanism for regulation of IL4 induced gene expression.
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