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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Acrosomal vesicle protein 1

SP-10, ACRV1, acrosomal protein SP-10, MSA-63
This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010] (from NCBI)
Papers on SP-10
Developmental expression of ACRV1 in humans and mice.
GeneRIF
Cai et al., Shenzhen, China. In Andrologia, 2012
Using RT-PCR analysis of mouse ACRV1, we determined that ACRV1 was expressed specifically in the testis, and its expression began at days 35.
TDP-43 is a transcriptional repressor: the testis-specific mouse acrv1 gene is a TDP-43 target in vivo.
GeneRIF
Reddi et al., Charlottesville, United States. In J Biol Chem, 2011
TDP-43 is a transcriptional repressor and that it regulates spatiotemporal expression of the acrv1 gene during spermatogenesis.
NF45 and NF90 in murine seminiferous epithelium: potential role in SP-10 gene transcription.
GeneRIF
Reddi et al., Charlottesville, United States. In J Androl, 2008
we propose that NF45 and NF90 have the potential to activate SP-10 gene transcription, and that a chromatin modification event must occur first in order to provide access to these transcription factors.
A novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: role for TDP-43 in insulator function.
GeneRIF
Reddi et al., Charlottesville, United States. In J Biol Chem, 2008
A novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: role for TDP-43 in insulator function.
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