sorting nexin 9
Input of microenvironmental regulation on colorectal cancer: role of the CCN family.
Taipei, Taiwan. In World J Gastroenterol, 2014
Many studies have shown that CCN members, such as CCN1, CCN2, CCN3, Wnt-induced secreted protein (WISP)-1, WISP-2, and WISP-3, are dysregulated in CRC, which implies potential diagnostic markers or therapeutic targets clinically.
Role of CCN, a vertebrate specific gene family, in development.
Tokyo, Japan. In Dev Growth Differ, 2009
CCN4, CCN5, and CCN6 were formerly reported to be in the Wisp family, but they are now integrated into CCN due to the resemblance of their four principal modules: insulin like growth factor binding protein, von Willebrand factor type C, thrombospondin type 1, and carboxy-terminal domain.