[BAG family gene and its relationship with lung adenocarcinoma susceptibility].
Tianjin, China. In Zhongguo Fei Ai Za Zhi, 2010
RESULTS: The expression levels of BAG-1, BAG-2, BAG-5 in cancer tissues were significantly downregulated compared with matched pericancerous lung tissues and were protective factors of lung adenocarcinoma (P < 0.05, OR < 1); while the expression level of BAG-4 in cancer tissues were remarkably upregulated compared with the matched pericancerous lung tissues and was risk factor of lung adenocarcinoma (P < 0.05, OR > 1).
Apoptosis: Silencing the death receptors.
Lausanne, Switzerland. In Curr Biol, 1999
An inhibitory protein has recently been identified, called silencer of death domains (SODD), that binds to the death domain of tumor necrosis factor receptor 1, thereby negatively regulating downstream signaling.