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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 21 May 2015.

SMT3 Smt3p

Smt3, SUMO, Smt3p, Pmt3
Top mentioned proteins: Ubiquitin, CAN, DAPI, SUMO-2, Ubc9
Papers using Smt3 antibodies
Evidence for heme-mediated redox regulation of human cystathionine beta-synthase activity.
Supplier
Cobine Paul, In PLoS ONE, 1997
... Aos1/ Uba2, Ubc9, SUMO-1 and SUMO-1 rabbit monoclonal antibody were purchased with the SUMOlink kit from Active Motif, Carlsbad, CA ...
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
Supplier
Malumbres Marcos et al., In Frontiers in Oncology, 1997
... SUMOylation of recombinant Aurora-A protein was tested using Active Motif SUMO link (Active Motif, #40120) and following manufacturer’s ...
SUMO-2/3 regulates topoisomerase II in mitosis
Supplier
Dasso Mary et al., In The Journal of Cell Biology, 1986
... The processed and full-length forms of SUMO-2 and -3 were cloned into pGEX4T-1, fused at their NH2 termini to an EGFP fragment that was excised from a pEGFP C-1 plasmid (CLONTECH Laboratories, Inc.) ...
Papers on Smt3
Increased SUMO-1 expression in response to hypoxia: Interaction with HIF-1α in hypoxic pulmonary hypertension.
New
Dai et al., Changsha, China. In Int J Mol Med, 14 Jun 2015
UNASSIGNED: Pulmonary hypertension (PH) develops in 30-70% of chronic obstructive pulmonary disease patients and increases morbidity and mortality.
USP11 Deubiquitinates Hybrid SUMO-Ubiquitin Chains to Counteract RNF4.
New
Vertegaal et al., Leiden, Netherlands. In J Biol Chem, 12 Jun 2015
UNASSIGNED: RNF4 is a SUMO-targeted ubiquitin E3 ligase with a pivotal function in the DNA damage response (DDR).
Minimal genomes of mycoplasma-related endobacteria are plastic and contain host-derived genes for sustained life within Glomeromycota.
New
Pawlowska et al., Ithaca, United States. In Proc Natl Acad Sci U S A, 11 Jun 2015
Some of these genes encode small ubiquitin-like modifier (SUMO) proteases specific to the SUMOylation systems of eukaryotes, which MRE likely use to manipulate their fungal host.
Ubiquitylation, neddylation and the DNA damage response.
Review
New
Jackson et al., Cambridge, United Kingdom. In Open Biol, 30 Apr 2015
Ubiquitin and the ubiquitin-like protein (UBL) SUMO have established roles in regulating the cellular response to DNA double-strand breaks (DSBs).
SUMO-mediated regulation of DNA damage repair and responses.
Review
New
Zhao et al., New York City, United States. In Trends Biochem Sci, 30 Apr 2015
Sumoylation has important roles during DNA damage repair and responses.
Interconnection between flowering time control and activation of systemic acquired resistance.
Review
New
Nandi et al., New Delhi, India. In Front Plant Sci, Dec 2014
SUMO conjugation and deconjugation mechanisms also similarly affect SAR and flowering in an SA-dependent manner.
Advances in the development of SUMO specific protease (SENP) inhibitors.
Review
New
Zhang et al., Yokohama, Japan. In Comput Struct Biotechnol J, Dec 2014
Sumoylation is a reversible post-translational modification that involves the covalent attachment of small ubiquitin-like modifier (SUMO) proteins to their substrate proteins.
Linking the SUMO protease SENP5 to neutrophil differentiation of AML cells.
New
Tschan et al., Bern, Switzerland. In Leuk Res Rep, Dec 2014
SENP5 is an enzyme that targets and cleaves small ubiquitin-like modifier (SUMO) residues from SUMOylated proteins.
High-level SAE2 promotes malignant phenotype and predicts outcome in gastric cancer.
New
Ji et al., Beijing, China. In Am J Cancer Res, Dec 2014
BACKGROUND: The SUMO pathway has been shown to play an important role in tumorigenesis.
Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction.
Review
New
Impact
Wilkinson et al., Bristol, United Kingdom. In Physiol Rev, Oct 2014
Hundreds of different proteins are SUMO substrates, and dysfunction of protein SUMOylation is implicated in a many different diseases.
Sumoylation pathway is required to maintain the basal breast cancer subtype.
New
Impact
Weigel et al., Iowa City, United States. In Cancer Cell, Jul 2014
Disruption of the sumoylation pathway by knockdown of sumoylation enzymes, mutation of the SUMO-target lysine of TFAP2A, or treatment with sumoylation inhibitors induced a basal-to-luminal transition, which was dependent on TFAP2A.
Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination.
New
Impact
Hunter et al., Davis, United States. In Nat Genet, Feb 2014
Designation of crossovers involves selective localization of the SUMO ligase RNF212 to a minority of recombination sites, where it stabilizes pertinent factors such as MutSγ (ref.
Cbx4 governs HIF-1α to potentiate angiogenesis of hepatocellular carcinoma by its SUMO E3 ligase activity.
New
Impact
Chen et al., Shanghai, China. In Cancer Cell, Feb 2014
Cbx4 is a polycomb group protein that is also a SUMO E3 ligase, but its potential roles in tumorigenesis remain to be explored.
Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modifications.
Review
Dragone et al., Aurora, United States. In Am J Clin Exp Immunol, 2013
This review will examine how ubiquitin, E3 ubiquitin ligases, and other ubiquitin-like modifications such as SUMO and NEDD8 regulate TCR complex-mediated signaling.
Control of nuclear activities by substrate-selective and protein-group SUMOylation.
Review
Impact
Psakhye et al., Martinsried, Germany. In Annu Rev Genet, 2012
Reversible modification of proteins by SUMO (small ubiquitin-like modifier) affects a large number of cellular processes.
Drosophila Smt3 negatively regulates JNK signaling through sequestering Hipk in the nucleus.
GeneRIF
Jiao et al., Beijing, China. In Development, 2011
although knockdown of the homeodomain-interacting protein kinase (Hipk) suppresses Smt3 depletion-induced activation of JNK, Hipk overexpression synergistically enhances this type of JNK activation
Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast.
GeneRIF
Perego et al., Milano, Italy. In Bmc Genomics, 2010
Data show that pmt3 mutants exhibiting hypersensitivity to cisplatin.
Role of the Zn(2+) motif of E1 in SUMO adenylation.
GeneRIF
Chen et al., Duarte, United States. In J Biol Chem, 2010
the Zn(2+) motif of E1 has a role in SUMO adenylation
Cdk1 and SUMO regulate Swe1 stability.
GeneRIF
Brandeis et al., Jerusalem, Israel. In Plos One, 2009
Cdk1 and SUMO (Smt3) regulate Swe1 stability
Genetic and proteomic evidence for roles of Drosophila SUMO in cell cycle control, Ras signaling, and early pattern formation.
GeneRIF
Courey et al., Los Angeles, United States. In Plos One, 2008
SUMO coordinates multiple regulatory processes during oogenesis and early embryogenesis
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