GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 14 Mar 2013.
SMT3 Smt3p
Smt3, SUMO, Smt3p, Pmt3
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Papers using
Smt3
antibodies
Evidence for heme-mediated redox regulation of human
cystathionine beta-synthase activity.
Supplier
In PLoS ONE, 1997
... Aos1/ Uba2, Ubc9, SUMO-1 and SUMO-1 rabbit monoclonal antibody were purchased with the SUMOlink kit from Active Motif, Carlsbad, CA ...
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
Supplier
In Frontiers in Oncology, 1997
... SUMOylation of recombinant Aurora-A protein was tested using Active Motif SUMO link (Active Motif, #40120) and following manufacturer’s ...
SUMO-2/3 regulates topoisomerase II in mitosis
Supplier
In The Journal of Cell Biology, 1986
... The processed and full-length forms of SUMO-2 and -3 were cloned into pGEX4T-1, fused at their NH2 termini to an EGFP fragment that was excised from a pEGFP C-1 plasmid (CLONTECH Laboratories, Inc.) ...
Papers on
Smt3
UBC9 regulates the stability of XBP1, a key transcription factor controlling the ER stress response.
New
Kyoto, Japan. In Cell Struct Funct, 07 Apr 2013
Here, we analyzed the regulatory mechanism of pXBP1(S) stability, and found that a SUMO-conjugase, UBC9, specifically bound to the leucine zipper motif of pXBP1(S) and increased the stability of pXBP1(S).
Development of a High-Throughput Screening Assay for Inhibitors of Small Ubiquitin-Like Modifier Proteases.
New
Durham, United States. In J Biomol Screen, 07 Apr 2013
Small ubiquitin-like modifier (SUMO1-3) is a small group of proteins that are ligated to lysine residues in target proteins.
SUMOylation affects the interferon blocking activity of the influenza A non-structural protein NS1 without affecting its stability or cellular localization.
New
El Paso, United States. In J Virol, 06 Apr 2013
Our pioneering studies on the interplay between the Small Ubiquitin-like MOdifier (SUMO) and influenza A virus identified the non-structural NS1 protein as the first known SUMO target of influenza virus and one of the most abundantly SUMOylated influenza proteins.
Secretory expression of lacticin Q fused with SUMO in Bacillus subtilis.
New
Beijing, China. In Protein Expr Purif, 05 Apr 2013
It may possibly be employed as an alternative to or in combination with nisin A. The objective of this study was to express lacticin Q extracellularly with Small ubiquitin-related modifier (SUMO) fusion technology in Bacillus subtilis.
Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation.
New
Shanghai, China. In Oncol Rep, 01 Apr 2013
Small ubiquitin-like modifier (SUMO) modification is an important post-translational protein modification that can be reversed by SUMO-specific proteases (SENPs); however, the physiological function of SENPs remains largely unexplored, and little is known about the regulation of SENPs themselves.
SUMO: a multifaceted modifier of chromatin structure and function.
Review
New
Baltimore, United States. In Dev Cell, 14 Feb 2013
A major challenge in nuclear organization is the packaging of DNA into dynamic chromatin structures that can respond to changes in the transcriptional requirements of the cell.
Function and regulation of SUMO proteases.
Review
New
Impact
New Haven, United States. In Nat Rev Mol Cell Biol, Dec 2012
Covalent attachment of small ubiquitin-like modifier (SUMO) to proteins is highly dynamic, and both SUMO-protein conjugation and cleavage can be regulated.
In Silico Structural and Functional Characterization of the RSUME Splice Variants.
New
Buenos Aires, Argentina. In Plos One, Dec 2012
RSUME (RWD-containing SUMO Enhancer) is a small protein that increases SUMO conjugation to proteins.
Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair.
New
Impact
Martinsried, Germany. In Cell, Dec 2012
Protein modification by SUMO affects a wide range of protein substrates.
Regulating the regulators: serine/arginine-rich proteins under scrutiny.
Review
New
Buenos Aires, Argentina. In Iubmb Life, Oct 2012
Towards the end, we focus in two recently revealed functions of SR proteins beyond mRNA biogenesis and metabolism, the regulation of micro-RNA processing and the regulation of small ubiquitin-like modifier (SUMO) conjugation.
SUMO, a heavyweight player in plant abiotic stress responses.
Review
New
Braga, Portugal. In Cell Mol Life Sci, Oct 2012
Over the last decade, the ubiquitin-like modifying peptide small ubiquitin-like modifier (SUMO) has been shown to regulate various nuclear processes, including transcriptional control.
SUMOylation in control of accurate chromosome segregation during mitosis.
Review
New
Detroit, United States. In Curr Protein Pept Sci, Aug 2012
Posttranslational protein modification by small ubiquitin-related modifier (SUMO) has emerged as an important regulatory mechanism for chromosome segregation during mitosis.
Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2.
New
Impact
New York City, United States. In Nature, Apr 2012
Ubiquitin (Ub) and ubiquitin-like (Ubl) modifiers such as SUMO (also known as Smt3 in Saccharomyces cerevisiae) mediate signal transduction through post-translational modification of substrate proteins in pathways that control differentiation, apoptosis and the cell cycle, and responses to stress such as the DNA damage response.
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.
New
Impact
Houston, United States. In Science, Feb 2012
To identify pathways supporting the Myc oncogenic program, we used a genome-wide RNA interference screen to search for Myc-synthetic lethal genes and uncovered a role for the SUMO-activating enzyme (SAE1/2).
The p53 mRNA-Mdm2 interaction controls Mdm2 nuclear trafficking and is required for p53 activation following DNA damage.
New
Impact
Paris, France. In Cancer Cell, Feb 2012
This event also promotes SUMO-conjugation of Mdm2 and its nucleoli accumulation.
Drosophila Smt3 negatively regulates JNK signaling through sequestering Hipk in the nucleus.
GeneRIF
Beijing, China. In Development, 2011
although knockdown of the homeodomain-interacting protein kinase (Hipk) suppresses Smt3 depletion-induced activation of JNK, Hipk overexpression synergistically enhances this type of JNK activation
Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast.
GeneRIF
Milano, Italy. In Bmc Genomics, 2010
Data show that pmt3 mutants exhibiting hypersensitivity to cisplatin.
Role of the Zn(2+) motif of E1 in SUMO adenylation.
GeneRIF
Duarte, United States. In J Biol Chem, 2010
the Zn(2+) motif of E1 has a role in SUMO adenylation
Cdk1 and SUMO regulate Swe1 stability.
GeneRIF
Jerusalem, Israel. In Plos One, 2009
Cdk1 and SUMO (Smt3) regulate Swe1 stability
Genetic and proteomic evidence for roles of Drosophila SUMO in cell cycle control, Ras signaling, and early pattern formation.
GeneRIF
Los Angeles, United States. In Plos One, 2008
SUMO coordinates multiple regulatory processes during oogenesis and early embryogenesis
