SUMO-2/3 regulates topoisomerase II in mitosis
In The Journal of Cell Biology, 1986
... The processed and full-length forms of SUMO-2 and -3 were cloned into pGEX4T-1, fused at their NH2 termini to an EGFP fragment that was excised from a pEGFP C-1 plasmid (CLONTECH Laboratories, Inc.) ...
DeSUMOylation: An Important Therapeutic Target and Protein Regulatory Event.
Wuhan, China. In Dna Cell Biol, 26 Sep 2015
UNASSIGNED: The discovery of the process of small ubiquitin-like modifier (SUMO)-mediated post-translational modification of targets (SUMOylation) in early 1990s proved to be a significant step ahead in understanding mechanistic regulation of proteins and their functions in diverse life processes at the cellular level.
Sumo and the cellular stress response.
Oslo, Norway. In Cell Div, Dec 2014
The ubiquitin family member Sumo has important functions in many cellular processes including DNA repair, transcription and cell division.
Direct and/or Indirect Roles for SUMO in Modulating Alpha-Synuclein Toxicity.
Gold Coast, Australia. In Biomolecules, Dec 2014
α-Synuclein inclusion bodies are a pathological hallmark of several neurodegenerative diseases, including Parkinson's disease, and contain aggregated α-synuclein and a variety of recruited factors, including protein chaperones, proteasome components, ubiquitin and the small ubiquitin-like modifier, SUMO-1.