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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Sterile alpha motif domain containing 8

SMSr, Sphingomyelin synthase-related protein SMSr
Top mentioned proteins: CD36, SM synthase, MOB, HAD, iMpact
Papers on SMSr
Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice.
Willecke et al., Bonn, Germany. In J Lipid Res, Apr 2015
Heterologous expression studies revealed that SM synthase (SMS)2 is a bifunctional enzyme producing both SM and CPE, whereas SMS-related protein (SMSr) serves as monofunctional CPE synthase.
All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity.
Jiang et al., Foshan, China. In J Lipid Res, Mar 2015
Sphingomyelin synthase-related protein (SMSr) synthesizes the sphingomyelin analog ceramide phosphoethanolamine (CPE) in cells.
Sphingomyelin synthase-related protein SMSr is a suppressor of ceramide-induced mitochondrial apoptosis.
Holthuis et al., Utrecht, Netherlands. In J Cell Sci, 2014
Here we identify SMSr (SAMD8), an ER-resident ceramide phosphoethanolamine (CPE) synthase, as a suppressor of ceramide-mediated cell death.
Mammalian ORMDL proteins mediate the feedback response in ceramide biosynthesis.
Wattenberg et al., Louisville, United States. In J Biol Chem, 2012
We also tested the atypical sphingomyelin synthase isoform, SMSr, for its role in the regulation of ceramide biosynthesis.
Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase.
Holthuis et al., Utrecht, Netherlands. In J Lipid Res, 2009
SM production is mediated by the SM synthases SMS1 in the Golgi and SMS2 at the PM, while a closely related enzyme, SMSr, has an unknown biochemical function.
Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER.
Holthuis et al., Utrecht, Netherlands. In J Cell Biol, 2009
In this study, we report the identification of an SMS1-related (SMSr) enzyme, which catalyses the synthesis of the SM analogue ceramide phosphoethanolamine (CPE) in the ER lumen.
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