smooth muscle alpha-actin
Tubular Compressed Collagen Scaffolds for Ureteral Tissue Engineering in a Flow Bioreactor System.
Lausanne, Switzerland. In Tissue Eng Part A, Sep 2015
This was confirmed by their gene expression of smooth muscle alpha-actin, smoothelin, collagen type I and III, elastin, laminin type 1 and 5, cytokeratin 8, and uroplakin 2. In addition, smooth muscle cell alignment predominantly perpendicular to the flow direction was observed, comparable to the cell orientation in native ureteral tissue.
[The phenotypic switching of vascular smooth muscle cells induced by cholesterol].
Shanghai, China. In Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 2014
Real-time quantitative PCR and Western blotting were respectively applied to detect the mRNA expressions of smooth muscle alpha-actin (α-SMA), smooth muscle 22 alpha (SM22α) and the protein expressions of SM22α, monocyte chemotactic protein-1 induced protein (MCPIP).
Chronic pancreatitis: potential future interventions.
Lund, Sweden. In Scand J Gastroenterol, 2010
During pancreatic injury or inflammation, quiescent stellate cells undergo a phenotypic transformation, characterized by smooth muscle alpha-actin expression and increased synthesis of extracellular matrix proteins.
F2-isoprostanes are not just markers of oxidative stress.
Siena, Italy. In Free Radic Biol Med, 2008
When hepatic stellate cells from normal liver were cultured up to activation (expression of smooth muscle alpha-actin) and then treated with F(2)-IsoPs in the concentration range found in the in vivo studies (10(-9) to 10(-8) M), a striking increase in DNA synthesis, cell proliferation, and collagen synthesis was observed.
MCAT elements and the TEF-1 family of transcription factors in muscle development and disease.
Charlottesville, United States. In Arterioscler Thromb Vasc Biol, 2008
MCAT elements are located in the promoter-enhancer regions of cardiac, smooth, and skeletal muscle-specific genes including cardiac troponin T, beta-myosin heavy chain, smooth muscle alpha-actin, and skeletal alpha-actin, and play a key role in the regulation of these genes during muscle development and disease.