A role for the mitogen-activated protein kinase kinase kinase 1 in epithelial wound healing.
In PLoS ONE, 2005
... as antibodies for phospho-c-Jun (Ser-63, 73), phospho-ATF2 (Thr-69, 71), phospho-p65 (Ser-536), phospho-SMAD2 (Ser-465, 467) and phospho-SMAD3 (Ser-423, 425), were purchased from Cell Signaling Technology (Danvers, MA); Antibodies ... TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivomore suppliers
In The American Journal of Pathology, 2004
... TAK1 (4505; Cell Signaling, Danvers, MA), phospho-TAK1 (4536; Cell Signaling), SMAD3 (ab29379; Abcam, Cambridge, UK), phospho-SMAD3 (ab52903; ...
Genetic variants in cell cycle control pathway confer susceptibility to aggressive prostate carcinoma.
Saint Louis, United States. In Prostate, 28 Jan 2016
RESULTS: Eleven variants within 10 genes (CCNC, CCND3, CCNG1, CCNT2, CDK6, MDM2, SKP2, WEE1, YWHAB, YWHAH) in the European-American population and nine variants in 7 genes (CCNG1, CDK2, CDK5, MDM2, RB1, SMAD3, TERF2) in the African-American population were found to be associated with aggressive PCa using at least one model.
Analysis of differentially expressed genes based on microarray data of glioma.
Nanjing, China. In Int J Clin Exp Med, 2014
In addition, the transcription factor analysis showed these DEGs were regulated by the binding sites of transcription factors GLI2, SP1, SMAD7, SMAD3, RELA, STAT5B, CTNNB1, STAT5A, TFAP2A and SP3.
Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm.
More papers using
Baltimore, United States. In Nat Genet, 2012
Loeys-Dietz syndrome (LDS) associates with a tissue signature for high transforming growth factor (TGF)-β signaling but is often caused by heterozygous mutations in genes encoding positive effectors of TGF-β signaling, including either subunit of the TGF-β receptor or SMAD3, thereby engendering controversy regarding the mechanism of disease.
Transforming growth factor-beta-induced inhibition of myogenesis is mediated through Smad pathway and is modulated by microtubule dynamic stability
In The Journal of Cell Biology, 2003
... (clone 9E10), SRF, CTGF (Santa Cruz Biotechnology, Inc.), GAPDH (EMD), histones, α1-integrin, paxillin (Millipore), PAI-1, Smad3 (Abcam), FAK, zonula occludens-1, phospho-FAK ...