Semaphorin 3A blocks the formation of pathologic choroidal neovascularization induced by transforming growth factor beta.
Beijing, China. In Mol Vis, Dec 2013
The proliferation, migration, apoptosis, and tube formation of the cells were then measured using BrdU, Transwell, flow cytometry, and Matrigel assays, respectively, and the SMAD2/3 signaling pathways were analyzed using western blot analysis.
Post-translational regulation of TGF-β receptor and Smad signaling.
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San Francisco, United States. In Febs Lett, 2012
TGF-beta family signaling through Smads is conceptually a simple and linear signaling pathway, driven by sequential phosphorylation, with type II receptors activating type I receptors, which in turn activate R-Smads [review]