Butein is a novel anti-adipogenic compound.
South Korea. In J Lipid Res, 06 Apr 2013
Small interfering RNA mediated silencing of STAT3 or SMAD2/3 blunted the inhibitory effects of butein on adipogenesis indicating that an interaction between two signaling pathways is required for the action of butein.
Evaluation of the prognostic value of pSMAD immunohistochemistry in colorectal cancer.
Utrecht, Netherlands. In Eur J Cancer Prev, 17 Mar 2013
As activation of the BMP and TGF-β pathways leads to phosphorylation of SMAD1,5,8 and SMAD2,3, respectively, and both need SMAD4 for translocation to the nucleus, we aimed to investigate whether nuclear staining of pSMAD1,5,8 and pSMAD2, 3 can be used as predictive markers in CRC.
More papers using
Paris, France. In Bull Cancer, 2010
These allelic losses are associated with mutations in TP53, APC, SMAD2 and SMAD4 genes.