Regulation of mitochondrial membrane permeabilization by BCL-2 family proteins and caspases
In BMC Gastroenterology, 2003
... (TRAIL) (BD Pharmingen, Franklin Lake, NJ, USA); antibodies against Bcl-2, Bax, Fas, Fas ligand (FasL), Smac/Diablo, and heat shock protein (HSP) 60 (Santa Cruz Biotechnology, Santa Cruz, CA, USA); ...
Mechanisms of TRAIL and gemcitabine induction of pancreatic cancer cell apoptosis.
Jinan, China. In Asian Pac J Cancer Prev, 2010
The levels of cellular apoptosis-associated proteins such as Smac/DIABLO, Cyto C, and the activated fragment of caspase-3 increased in pancreatic cancer cells, but the expression of XIAP was significantly decreased after 24 h treatment with the combination of TRAIL and gemcitabine.