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MIF4G domain containing

SLIP1, MIFD, MIF4G domain-containing protein
This gene encodes a protein which interacts with the N-terminus of the stem-loop binding protein (SLBP) and the 3' end of histone mRNA. This interaction facilitates the activation of histone mRNA translation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011] (from NCBI)
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Papers on SLIP1
INT6 interacts with MIF4GD/SLIP1 and is necessary for efficient histone mRNA translation.
Jalinot et al., Lyon, France. In Rna, 2012
INT6 and MIF4GD were observed to colocalize in cytoplasmic foci. It was concluded that INT6, by establishing interactions with MIF4GD and SLBP, plays an important role in translation of poly(A) minus histone mRNAs.
SLIP1, a factor required for activation of histone mRNA translation by the stem-loop binding protein.
Marzluff et al., Chapel Hill, United States. In Mol Cell Biol, 2008
downregulation of endogenous SLIP1 reduces the rate of translation of endogenous histone mRNA and also reduces cell viability.
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