Human SLC4A11 Is a Novel NH3/H+ Co-transporter.
Indianapolis, United States. In J Biol Chem, Aug 2015
SLC4A11 has been proposed to be an electrogenic membrane transporter, permeable to Na(+), H(+) (OH(-)), bicarbonate, borate, and NH4 (+).
Fuchs Corneal Dystrophy.
Baltimore, United States. In Prog Mol Biol Transl Sci, 2014
Multiple chromosomal loci and, more recently, causal genetic mutations have been identified for this complex disorder, including in TCF8, SLC4A11, LOXHD1, and AGBL1.
Regulators of Slc4 bicarbonate transporter activity.
Birmingham, United States. In Front Physiol, 2014
The Slc4 family of transporters is comprised of anion exchangers (AE1-4), Na(+)-coupled bicarbonate transporters (NCBTs) including electrogenic Na/bicarbonate cotransporters (NBCe1 and NBCe2), electroneutral Na/bicarbonate cotransporters (NBCn1 and NBCn2), and the electroneutral Na-driven Cl-bicarbonate exchanger (NDCBE), as well as a borate transporter (BTR1).