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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3

SLC35A3, solute carrier family 35 member 3, UDP-N-acetylglucosamine transporter, Golgi UDP-GlcNAc transporter
Top mentioned proteins: ACID, POLYMERASE, CAN, HAD, UGT
Papers on SLC35A3
UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats).
New
Olczak et al., Wrocław, Poland. In J Biol Chem, Jul 2015
UDP-galactose transporter (UGT; SLC35A2) and UDP-N-acetylglucosamine transporter (NGT; SLC35A3) form heterologous complexes in the Golgi membrane.
Identification of a Golgi-localized UDP-N-acetylglucosamine transporter in Trypanosoma cruzi.
Ramos et al., São Paulo, Brazil. In Bmc Microbiol, 2014
A UDP-N-acetylglucosamine transporter, TcNST1, was identified by a yeast complementation approach.
Short N-terminal region of UDP-galactose transporter (SLC35A2) is crucial for galactosylation of N-glycans.
Olczak et al., Wrocław, Poland. In Biochem Biophys Res Commun, 2014
UDP-galactose transporter (UGT) and UDP-N-acetylglucosamine transporter (NGT) form heterologous complexes in the Golgi apparatus (GA) membrane.
Mutations in SLC35A3 cause autism spectrum disorder, epilepsy and arthrogryposis.
Elpeleg et al., Jerusalem, Israel. In J Med Genet, 2013
METHODS AND RESULTS: By linkage analysis and exome sequencing, we identified deleterious mutations in SLC35A3 in these patients.
UDP-N-acetylglucosamine transporter (SLC35A3) regulates biosynthesis of highly branched N-glycans and keratan sulfate.
Olczak et al., Wrocław, Poland. In J Biol Chem, 2013
SLC35A3 is considered the main UDP-N-acetylglucosamine transporter (NGT) in mammals.
UDP-Gal/UDP-GlcNAc chimeric transporter complements mutation defect in mammalian cells deficient in UDP-Gal transporter.
Olczak et al., Wrocław, Poland. In Biochem Biophys Res Commun, 2013
The role of UDP-galactose transporter (UGT; SLC35A2) and UDP-N-acetylglucosamine transporter (NGT; SLC35A3) in glycosylation of macromolecules may be coupled and either of the transporters may partially replace the function played by its partner.
Detection of haplotypes associated with prenatal death in dairy cattle and identification of deleterious mutations in GART, SHBG and SLC37A2.
Boichard et al., Paris, France. In Plos One, 2012
Six strong candidate causative mutations including polymorphisms previously reported in FANCI (Brachyspina), SLC35A3 (CVM), APAF1 (HH1) and three novel mutations with very damaging effect on the protein structure, according to SIFT and Polyphen-2, were detected in GART, SHBG and SLC37A2 genes.
UDP-N-acetylglucosamine transporter and UDP-galactose transporter form heterologous complexes in the Golgi membrane.
Olczak et al., Wrocław, Poland. In Febs Lett, 2012
UDP-galactose transporter (UGT; SLC35A2) and UDP-N-acetylglucosamine transporter (NGT; SLC35A3) are evolutionarily related.
Differential expression of select members of the SLC family of genes and regulation of expression by microRNAs in the chicken oviduct.
Bazer et al., Seoul, South Korea. In Biol Reprod, 2012
Expression of SLC1A4 (glutamate and neutral amino acid transporter), SLC13A2 (dicarboxylate transporter), and SLC35B4 (UDP-xylose: UDP-N-acetylglucosamine transporter) mRNAs was limited to glandular epithelium (GE), while SLC4A5 (sodium bicarbonate cotransporter) and SLC7A3 (cationic amino acid transporter) mRNAs were expressed predominantly in the luminal epithelium of the magnum.
Functional analysis of a Hansenula polymorpha MNN2-2 homologue encoding a putative UDP-N-acetylglucosamine transporter localized in the endoplasmic reticulum.
Kang et al., Seoul, South Korea. In J Microbiol, 2011
The Kluyveromyces lactis UDP-GlcNAc transporter (KlMnn2-2p) is responsible for the biosynthesis of N-glycans containing N-acetylglucosamine.
Identification of complex vertebral malformation carriers in Holstein cattle in south China.
Zhang et al., Wuhan, China. In Genet Mol Res, 2010
Guanine is substituted by thymine (G>T) in the solute carrier family 35 member A3 gene (SLC35A3).
[Identification of the complex vertebral malformation gene in Chinese Holstein and its association with dairy performance traits].
Zhang et al., Beijing, China. In Yi Chuan, 2010
Complex vertebral malformation is caused by a single base mutation from G to T at the nucleotide position 559 in the bovine solute carrier family 35 member 3 (SLC35A3) gene exon 4 on Bos Taurus autosome (BTA) 3. The presence of the disease gene in Holstein dairy cattle has been reported in many countries.
[Vertebral and multiple organ malformations in a black and white German Holstein calf].
Distl et al., Hannover, Germany. In Berl Munch Tierarztl Wochenschr, 2010
Due to the exclusion of a point mutation in exon 4 of the solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 (SLC35A3) gene, complex vertebral malformation (CVM) was ruled out.
Neospora caninum and complex vertebral malformation as possible causes of bovine fetal mummification.
Nishibori et al., Hiroshima, Japan. In Can Vet J, 2009
Fifteen mummified fetuses were tested by polymerase chain reaction (PCR) for the mutation in the bovine SLC35A3 gene that causes complex vertebral malformation (CVM) and the pNC-5 gene which identifies N. caninum infection.
[The development and application of method for detecting bovine complex vertebral malformation].
Zhong et al., China. In Yi Chuan, 2008
The molecular cause of CVM was a substitution of guanine by thymine (G-->T) in a solute carrier family 35 member 3 gene (SLC35A3), encoding UDP-N-acetylglucosamine transporter.
Evaluation of SLC35A3 as a candidate gene for human vertebral malformations.
GeneRIF
Giampietro et al., Marshfield, United States. In Am J Med Genet A, 2006
SLC35A3 is an unlikely candidate for the pathogenesis of vertebral malformations because no mutation was found in this cohort study.
A missense mutation in the bovine SLC35A3 gene, encoding a UDP-N-acetylglucosamine transporter, causes complex vertebral malformation.
GeneRIF
Bendixen et al., Denmark. In Genome Res, 2006
A mutation in the SLC35A3 gene is associated with vertebral malformations in cattle. A missense mutation likely effects signal transduction which relies on glycosylation.
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