skeletal troponin C
Fast pressure jumps can perturb calcium and magnesium binding to troponin C F29W.
Canterbury, United Kingdom. In Biochemistry, 2008
We have used rapid pressure jump and stopped-flow fluorometry to investigate calcium and magnesium binding to F29W chicken skeletal troponin C. Increased pressure perturbed calcium binding to the N-terminal sites in the presence and absence of magnesium and provided an estimate for the volume change upon calcium binding (-12 mL/mol).
Molecular basis for the influence of muscle length on myocardial performance.
United States. In Science, 1988
To seek the molecular explanation of this effect, a study was made of the effects of length on Ca2+ sensitivity during tension development by isolated demembranated cardiac muscle in which the cardiac form of troponin C was substituted with skeletal troponin C. The results of troponin C exchange were compared at sarcomere lengths of 1.9 and 2.4 micrometers.