Integrin signalling and function in immune cells.
Shanghai, China. In Immunology, 2012
This review discusses the key signalling complexes regulating integrin activation and function in both 'inside-out' and 'outside-in' pathways in T lymphocytes, including kinases, SLP-76, VAV1, ADAP, SKAP-55, RapL, RIAM, Rap1, Talin and Kindlin.
Adaptors and linkers in T and B cells.
Magdeburg, Germany. In Curr Opin Immunol, 2004
Finally, an involvement of the cytosolic adaptors ADAP, SKAP-55 and Cbl-b in the regulation of lymphocyte adhesion and migration has been demonstrated.
T-cell integrins: more than just sticking points.
London, United Kingdom. In J Cell Sci, 2004
Signalling pathways involving ADAP, Vav-1 and SKAP-55, as well as Rap1 and RAPL, cause clustering of leukocyte function-associated antigen-1 (LFA-1; integrin alphaLbeta2).