Differential expression of retinal determination genes in the principal and secondary eyes of Cupiennius salei Keyserling (1877).
Vienna, Austria. In Evodevo, 2014
Later in development (180 to 280 h after egg laying), there is differential expression of the genes in disparate eye vesicles; for example, Cs-otxa is expressed only in posterior-lateral eye vesicles, Cs-otxb, Cs-six1a, and Cs-six3b in all three secondary eye vesicles, Cs-pax6a only in principal eye vesicles, Cs-six1b in posterior-median, and posterior-lateral eye vesicles, and Cs-six3a in lateral and principal eye vesicles.
SIX2 Effects on Wilms Tumor Biology.
Nashville, United States. In Transl Oncol, 2014
Sine oculis homeobox 2 (SIX2) is a transcription factor expressed specifically in the CM, provides a critical mechanism for CM self-renewal, and remains persistently active in WT blastema, although its purpose in this childhood malignancy remains unclear.
Uncapping the potential of renal stem cells.
Toronto, Canada. In Cell Stem Cell, 2008
six2-expressing mesenchymal cells exhibit hallmark stem cell traits, in that they appear to self-renew and are clonally multipotent for a range of nephron epithelial cell types.