SIRT6, oxidative stress, and aging.
Novato, United States. In Cell Res, Feb 2016
A new study published in Cell Research reports a novel role for the aging-associated SIRT6 deacetylase in the control of oxidative homeostasis in human mesenchymal stem cells.
The complex role of SIRT6 in carcinogenesis.
Ramat Gan, Israel. In Carcinogenesis, Jan 2016
UNASSIGNED: SIRT6, a member of the mammalian sirtuins family, functions as a mono-ADP-ribosyl transferase and NAD(+)-dependent deacylase of both acetyl groups and long-chain fatty acyl groups.
The role of sirtuins in cardiac disease.
Newark, United States. In Am J Physiol Heart Circ Physiol, Nov 2015
Sirt6 has also recently been demonstrated to attenuate cardiac hypertrophy, and Sirt7 is known to regulate apoptosis and stress responses in the heart.