Clinical applications of gene therapy for primary immunodeficiencies.
Milano, Italy. In Hum Gene Ther, Apr 2015
On the other hand, the occurrence of insertional oncogenesis in SCID-X1, WAS, and chronic granulomatous disease (CGD) RV clinical trials prompted the development of safer vector construct based on self-inactivating (SIN) retroviral or lentiviral vectors (LVs).
Regulation of cytokinesis by spindle-pole bodies.
Albany, United States. In Nat Cell Biol, 2006
In the fission yeast Schizosaccharomyces pombe, cytokinesis is thought to be controlled by the daughter spindle-pole body (SPB) through a regulatory pathway named the septation initiation network (SIN).