[Relationship between macrophages and erythropoiesis].
Tianjin, China. In Zhongguo Dang Dai Er Ke Za Zhi, Jan 2016
A recent mouse study has demonstrated that the phenotype of macrophages in erythroblastic islands is CD169(+) VCAM-1(+) ER-HR3(+) CD11b(+) F4/80(+) Ly-6G(+).
PRRS virus receptors and their role for pathogenesis.
Urbana, United States. In Vet Microbiol, Jul 2015
At least six cellular molecules have been described so far as putative receptors for PRRSV, and they include heparan sulfate, vimentin, CD151, sialoadhesin (CD169; siglec-1), dendritic cell-specific intercellular adhesion melecule-3-grabbing non-integrin (DC-SIGN; CD209), and CD163 (SRCR, cysteine-rich scavenger receptor).
CD169-dependent cell-associated HIV-1 transmission: a driver of virus dissemination.
Boston, United States. In J Infect Dis, 2015
We will evaluate the role of CD169 as a DC-associated HIV-1 attachment factor, investigate the molecular mechanisms by which HIV-1 particles are transferred from DCs to CD4(+) T cells across virological synapses, and provide arguments for inclusion of molecules in microbicides that can effectively target HIV-1 attachment to DCs and DC-mediated virus transfer.
Cognitive consequences of a sustained monocyte type 1 IFN response in HIV-1 infection.
San Francisco, United States. In Curr Hiv Res, 2013
An IFN "alarm" signature, defined as monocyte activation with overexpression of the type1 IFN genes IFI27 and CD169, would be useful for identifying a subset of subjects with HIV-1 infection that could progress to a number of pathologies associated with immune activation including cognitive dysfunction.