SH3 domain-binding protein
Apollon/Bruce is upregulated by Humanin.
Tokyo, Japan. In Mol Cell Biochem, 2014
A previous study demonstrated that the Humanin-induced activation of the htHNR/JAK2/STAT3 signaling pathway leads to increased expression of SH3 domain-binding protein 5 (SH3BP5), which is an essential effector of Humanin's anti-cell death activity in some cultured neuronal cells.
Fukui, Japan. In Nihon Rinsho, 2013
Furthermore, we will introduce our findings of the adaptor protein 3BP2 (c-Abl SH3 domain-binding protein-2), as a novel target of Syk.