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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Shugoshin-like 1

Sgo1, SGO, Shugoshin
Top mentioned proteins: CAN, Aurora, HAD, PP2A, Bub1
Papers using Sgo1 antibodies
Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2
Gruneberg Ulrike et al., In The Journal of Cell Biology, 2009
... rabbit anti-Myc (both from Sigma-Aldrich), mouse anti-Plk1 (Santa Cruz Biotechnology, Inc.), mouse anti-PPP2CA (BD), mouse anti-Sgo1 (Abcam), rabbit anti-Sgo2 (Bethyl Laboratories, ...
Papers on Sgo1
SGO1C is a non-functional isoform of Shugoshin and can disrupt sister chromatid cohesion by interacting with PP2A-B56.
Poon et al., Hong Kong, Hong Kong. In Cell Cycle, Jan 2016
Shugoshin (SGO1) plays a pivotal role in sister chromatid cohesion during mitosis by protecting the centromeric cohesin from mitotic kinases and WAPL.
Comparison of cone-beam computed tomography cephalometric measurements using a midsagittal projection and conventional two-dimensional cephalometric measurements.
Moon et al., Inch'ŏn, South Korea. In Korean J Orthod, Nov 2015
LCR was significantly different from 3 types of CBCT in 3 angular (SN to FH, interincisal angle, FMIA) and 2 linear (S-Go, Co-ANS) measurements.
A high-performance moisture sensor based on ultralarge graphene oxide.
Hong et al., Inch'ŏn, South Korea. In Nanoscale, Nov 2015
The GO size effect on the humidity sensing performance was evaluated on gold electrodes drop-coated with either an ultralarge graphene oxide (UGO) sheet (lateral size = 47.4 ± 22.2 μm) or a small-sized graphene oxide (SGO) sheet (lateral size = 0.8 ± 0.5 μm).
Relationship Between the Thickness of Cortical Bone at Maxillary Mid-palatal Area and Facial Height Using CBCT.
Saeedi et al., Tabrīz, Iran. In Open Dent J, 2014
In order to determine which patient belongs to which facial height category, i.e. normal, long or short, two angular and linear evaluations were used: the angle between S-N and Go-Me lines and the S-Go/N-Me ratio.
Cephalometric Analysis of the Facial Skeletal Morphology of Female Patients Exhibiting Skeletal Class II Deformity with and without Temporomandibular Joint Osteoarthrosis.
Yi et al., Beijing, China. In Plos One, 2014
The cephalometric measurements that represented skeletal characteristics, including mandibular position relative to the cranial base, mandibular plane angle (MP-SN), posterior facial height (S-Go), and facial height ratio, were significantly different among the three groups (p < 0.05).
Phosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis.
Yu et al., Dallas, United States. In Nat Cell Biol, 2013
The complex of shugoshin and protein phosphatase 2A (SGO1-PP2A) protects cohesin at centromeres from premature removal by mitotic kinases and WAPL in prophase.
Shugoshins: from protectors of cohesion to versatile adaptors at the centromere.
Pendás et al., Salamanca, Spain. In Trends Genet, 2012
Shugoshin proteins protect cohesin from cleavage by separase during meiosis I in eukaryotes and from phosphorylation-mediated removal during mitosis in vertebrates.
Lentivirus-mediated siRNA interference targeting SGO-1 inhibits human NSCLC cell growth.
Zhang et al., Xi'an, China. In Tumour Biol, 2012
Lentivirus-mediated siRNA interference targeting SGO-1 inhibits human NSCLC cell growth
Bub1 kinase and Sgo1 modulate pericentric chromatin in response to altered microtubule dynamics.
Bloom et al., Chapel Hill, United States. In Curr Biol, 2012
Bub1 and Sgo1 act as a rheostat to regulate the chromatin spring and maintain force balance. Through histone H2A S121 phosphorylation and recruitment of Sgo1, Bub1 kinase softens the chromatin spring in response to changes in microtubule dynamics.
Haploinsufficiency of SGO1 results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis.
Rao et al., Oklahoma City, United States. In Cell Cycle, 2012
Haploinsufficiency of SGO1 results in genomic instability manifested as missegregation of chromosomes and formation of extra centrosomal foci in both murine embryonic fibroblasts and adult bone marrow cells.
A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion.
Sugimura et al., Hamamatsu, Japan. In Oncogene, 2011
These results suggest that SGOL1-P1 may function as a negative factor to native SGOL1, and that abundant expression of SGOL1-P1 may be responsible for chromosomal instability.
Bub1, Sgo1, and Mps1 mediate a distinct pathway for chromosome biorientation in budding yeast.
Pellman et al., Boston, United States. In Mol Biol Cell, 2011
found that Sgo1 overexpression rescues defects caused by metaphase inactivation of Mps1 and that Mps1 is required for Sgo1 localization to the kinetochore
Shugoshin-PP2A counteracts casein-kinase-1-dependent cleavage of Rec8 by separase.
Watanabe et al., Tokyo, Japan. In Nat Cell Biol, 2010
balance between Rec8 phosphorylation and its dephosphorylation by Sgo1-PP2A regulates the step-wise loss of chromosomal cohesion in meiosis
Fused sister kinetochores initiate the reductional division in meiosis I.
Dawe et al., Athens, United States. In Nat Cell Biol, 2009
Several data suggest that sister kinetochores co-orient early in metaphase I and that sister chromatid cohesion (which requires Rec8 and Shugoshin) supports monopolar orientation.
The many faces of shugoshin, the "guardian spirit," in chromosome segregation.
Yu et al., Tallahassee, United States. In Cell Cycle, 2009
Since it was first identified in Drosophila as a centromeric protein, MEI-S332/Shugoshin (Sgo1) has been an enigma.
Solving the shugoshin puzzle.
Rumpf et al., Vienna, Austria. In Trends Genet, 2008
Shugoshin proteins form a complex with protein phosphatase 2A (PP2A) that protects centromeric cohesin from separase-mediated cleavage during yeast meiosis I. Recent work shows that this mechanism is conserved from yeast to mammals.
Bub1: escapades in a cellular world.
Gjoerup et al., Boston, United States. In Cell Cycle, 2007
Thus, Bub1 is required for assembly of a functional inner centromere, sister chromatid cohesion via targeting of the Shugoshin protein, and metaphase congression.
Shugoshin and PP2A, shared duties at the centromere.
Losada et al., Madrid, Spain. In Bioessays, 2006
Shugoshin (Sgo) protects centromeric cohesin from dissociation in early mitosis and from cleavage by separase in meiosis I. Three exciting new reports indicate that this is accomplished by recruiting the serine/threonine protein phosphatase 2A (PP2A) to centromeres.((1-3))
Shugoshin collaborates with protein phosphatase 2A to protect cohesin.
Watanabe et al., Tokyo, Japan. In Nature, 2006
a specific subtype of serine/threonine protein phosphatase 2A (PP2A) associates with human shugoshin
The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.
Murray et al., Cambridge, United States. In Science, 2005
Sgo1 is required for sensing tension between sister chromatids during mitosis, and its degradation when they separate may prevent cell cycle arrest and chromosome loss in anaphase, a time when sister chromatids are no longer under tension
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