Cytotoxic Effect of Fluvastatin on MCF-7 Cells Possibly Through a Reduction of the mRNA Expression Levels of SGK1 and CAV1.
Samsun, Turkey. In Cancer Biother Radiopharm, 27 Nov 2014
At the same time, we measured the mRNA expression levels of glucose-regulated protein 78 (GRP78), CCAAT/enhancer binding protein, homologous protein (CHOP), caveolin-1 (CAV1), NDRG1 Variant 1 and Variant 2, HMOX1, SGK1, and prostate apoptosis response-4 (PAR4) genes using quantitative real-time polymerase chain reaction (LightCycler 480 II).
The sodium chloride cotransporter SLC12A3: new roles in sodium, potassium, and blood pressure regulation.
Rotterdam, Netherlands. In Pflugers Arch, Jan 2014
This complex network consists of kinases and ubiquitinases, including WNKs, SGK1, SPAK, Nedd4-2, Cullin-3, and Kelch-like 3. The pathophysiological significance of this network is illustrated by the fact that modification of each individual protein in the network changes NCC activity and results in salt-dependent hypotension or hypertension.
[Function of mTORC2 and its roles in hematological malignancies].
Tianjin, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, Aug 2013
By means of activating AKT, PKCα, SGK1 and so on, the mTORC regulates many vital activities:embryonic development, cytoskeletal reconstitution,cell migration and protein post-translational modification.