Coevolutionary patterning of teeth and taste buds.
London, United Kingdom. In Proc Natl Acad Sci U S A, Dec 2015
sfrp5 and bmper, notable for roles in Wingless (Wnt) and bone morphogenetic protein (BMP) signaling, were differentially expressed across cichlid species with divergent tooth and taste bud density, and were expressed in the development of both organs in mice.
Obesity, inflammation, and lung injury (OILI): the good.
Buffalo, United States. In Mediators Inflamm, 2013
To sum up, the majority of evidence supported that adiponectin, omentin, and secreted frizzled-related protein 5 (SFRP5) were reduced significantly in obesity, which is associated with increased inflammation, indicated by increase of TNF α and IL-6, through activation of toll-like receptor (TLR4) and nuclear factor light chain κ B (NF- κ B) signaling pathways.
Genetic and epigenetic alteration in gastric carcinogenesis.
Porto, Portugal. In Helicobacter, 2010
Several genes have been newly associated with gastric carcinogenesis, both through oncogenic activation (MYC, SEMA5A, BCL2L12, RBP2 and BUBR1) and tumor suppressor gene inactivation mechanisms (KLF6, RELN, PTCH1A, CLDN11, and SFRP5).