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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

SCAN domain containing 1

SDP1, SCAN domain-containing, RAZ1, SUGAR-DEPENDENT1, SCAND1
This gene encodes a SCAN box domain-containing protein. The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. This protein binds to and may regulate the function of the transcription factor myeloid zinc finger 1B. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011] (from NCBI)
Top mentioned proteins: ACID, CAN, V1a, iMpact, HAD
Papers on SDP1
Zscan10 is dispensable for maintenance of pluripotency in mouse embryonic stem cells.
New
Niwa et al., Kōbe, Japan. In Biochem Biophys Res Commun, Jan 2016
Zinc finger and SCAN domain-containing 10 (Zscan10, also known as Zfp206) encodes a transcription factor that has been reported to be involved in the maintenance of pluripotency in mouse embryonic stem (ES) cells.
Peroxisome extensions deliver the Arabidopsis SDP1 lipase to oil bodies.
New
Gaude et al., Lyon, France. In Proc Natl Acad Sci U S A, May 2015
In the model plant Arabidopsis thaliana, Sugar-Dependent 1 (SDP1) was identified as the major TAG lipase involved in lipid reserve mobilization during seedling establishment.
Arabidopsis lipins, PDAT1 acyltransferase, and SDP1 triacylglycerol lipase synergistically direct fatty acids toward β-oxidation, thereby maintaining membrane lipid homeostasis.
Xu et al., New York City, United States. In Plant Cell, 2014
Using the trigalactosyldiacylglycerol1-1 (tgd1-1) mutant, which displays substantially enhanced PDAT1-mediated TAG synthesis, we demonstrate that disruption of SUGAR-DEPENDENT1 (SDP1) TAG lipase or PEROXISOMAL TRANSPORTER1 (PXA1) severely decreases FA turnover, leading to increases in leaf TAG accumulation, to 9% of dry weight, and in total leaf lipid, by 3-fold.
Zscan4 interacts directly with human Rap1 in cancer cells regardless of telomerase status.
Gollahon et al., Lubbock, United States. In Cancer Biol Ther, 2014
Recently, the newly identified embryonic stem cell marker, Zinc finger and SCAN domain-containing 4 gene (Zscan4), was shown to be a telomere-associated protein, co-localizing to the shelterin complex.
Multigene engineering of triacylglycerol metabolism boosts seed oil content in Arabidopsis.
Eastmond et al., Harpenden, United Kingdom. In Plant Physiol, 2014
Using Arabidopsis (Arabidopsis thaliana) as an experimental system, we show that seed-specific overexpression of WRINKLED1 (a transcriptional regulator of glycolysis and fatty acid synthesis) and DIACYLGLYCEROL ACYLTRANSFERASE1 (a triacylglycerol biosynthetic enzyme) combined with suppression of the triacylglycerol lipase SUGAR-DEPENDENT1 results in a higher percentage seed oil content and greater seed mass than manipulation of each gene individually.
Gene silencing of Sugar-dependent 1 (JcSDP1), encoding a patatin-domain triacylglycerol lipase, enhances seed oil accumulation in Jatropha curcas.
Chua et al., New York City, United States. In Biotechnol Biofuels, 2013
SDP1 is a specific lipase for the first step of TAG catabolism in Arabidopsis seeds.
The sugar-dependent1 lipase limits triacylglycerol accumulation in vegetative tissues of Arabidopsis.
Eastmond et al., Coventry, United Kingdom. In Plant Physiol, 2013
Here, we show that disruption of TAG hydrolysis in the Arabidopsis (Arabidopsis thaliana) lipase mutant sugar-dependent1 (sdp1) leads to a substantial accumulation of TAG in roots and stems but comparatively much lower TAG accumulation in leaves.
Suppression of the SUGAR-DEPENDENT1 triacylglycerol lipase family during seed development enhances oil yield in oilseed rape (Brassica napus L.).
Eastmond et al., Coventry, United Kingdom. In Plant Biotechnol J, 2013
Here, we show that RNAi suppression of the SUGAR-DEPENDENT1 triacylglycerol lipase gene family during seed development results in up to an 8% gain in oil yield on either a seed, plant or unit area basis in the greenhouse, with very little adverse impact on seed vigour.
Exposure to Maternal Diabetes in Utero and DNA Methylation Patterns in the Offspring.
Dabelea et al., Aurora, United States. In Immunometabolism, 2013
Among the top 10 ranked DMRs, we identified several genes, including NPR1, PANK1, SCAND1, and GJA4, which are known to be associated with cardiometabolic traits.
Transcriptional repression of VEGF by ZNF24: mechanistic studies and vascular consequences in vivo.
Moses et al., Boston, United States. In Blood, 2013
We have previously reported the identification of a SCAN domain-containing C2H2 zinc finger protein, ZNF24, that represses the transcription of VEGF.
Clinical application of RT-nested PCR integrated with RFLP in Hantavirus detection and genotyping: a prospective study in Shandong Province, PR China.
Yao et al., Beijing, China. In Cell Biochem Biophys, 2012
Sequence phylogenetic analysis of RT-nested PCR amplicons revealed sdp1, sdp2 YXL-2008, and sdp3 as close relatives of HTNV strain 76-118, while sdp22 and sdp37 as close relatives of SEOV strain Z37 and strain R22 located in two separate clusters in the phylogenetic tree.
An AT-hook gene is required for palea formation and floral organ number control in rice.
Zhu et al., Beijing, China. In Dev Biol, 2011
Both the sterile lemma elongation and the floral organ number increase phenotype are enhanced by the mutation of an independent gene SMALL DEGENERATIVE PALEA1 (SDP1), whose single mutation causes reduced palea size.
Seed storage oil mobilization is important but not essential for germination or seedling establishment in Arabidopsis.
GeneRIF
Eastmond et al., Warwick, United Kingdom. In Plant Physiol, 2011
together SDP1 and SDP1L account for at least 95% of the rate of triacylglycerol hydrolysis in Arabidopsis seeds, and that this hydrolysis is important but not essential for seed germination or seedling establishment.
Genomic targets of the KRAB and SCAN domain-containing zinc finger protein 263.
Farnham et al., Davis, United States. In J Biol Chem, 2010
Half of all human transcription factors use C2H2 zinc finger domains to specify site-specific DNA binding and yet very little is known about their role in gene regulation.
Storage oil hydrolysis during early seedling growth.
Review
Eastmond et al., Warwick, United Kingdom. In Plant Physiol Biochem, 2009
We then discuss some of the biochemical literature on seed lipases and describe the cloning and characterisation of a lipase called SUGAR-DEPENDENT1, which is required for TAG breakdown in Arabidopsis thaliana seeds.
Spectroscopic characterization of the tumor antigen NY-REN-21 and identification of heterodimer formation with SCAND1.
GeneRIF
Zanchin et al., Campinas, Brazil. In Biochem Biophys Res Commun, 2006
This result indicates that NY-REN-21 can function either as a homodimer or as a heterodimer with SCAND1.
SUGAR-DEPENDENT1 encodes a patatin domain triacylglycerol lipase that initiates storage oil breakdown in germinating Arabidopsis seeds.
GeneRIF
Eastmond, York, United Kingdom. In Plant Cell, 2006
SDP1 encodes a lipase that initiates oil breakdown in germinating Arabidopsis seeds. [SDP1]
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