Disruption of Scube2 Impairs Endochondral Bone Formation.
Taipei, Taiwan. In J Bone Miner Res, Jul 2015
Signal peptide-CUB-EGF domain-containing protein 2 (SCUBE2) belongs to a secreted and membrane-tethered multidomain SCUBE protein family composed of three members found in vertebrates and mammals.
Co-expression of genes with estrogen receptor-α and progesterone receptor in human breast carcinoma tissue.
In Horm Mol Biol Clin Investig, 2012
Coordinate expression of EVL, NAT1, TBC1D9, SCUBE2, RABEP1, SLC39A6, TCEAL1, FUT8, XBP1, PTP4A2 or GATA3 with either ESR1 or PGR was detected.
Interrogating differences in expression of targeted gene sets to predict breast cancer outcome.
Louisville, United States. In Bmc Cancer, 2012
RESULTS: Univariate analyses revealed over-expression of RABEP1, PGR, NAT1, PTP4A2, SLC39A6, ESR1, EVL, TBC1D9, FUT8, and SCUBE2 were all associated with reduced time to disease-related mortality (HR between 0.8 and 0.91, adjusted p < 0.05), while RABEP1, PGR, SLC39A6, and FUT8 were also associated with reduced recurrence times.
Clinical implications of gene dosage and gene expression patterns in diploid breast carcinoma.
Göteborg, Sweden. In Clin Cancer Res, 2010
In addition, more malignant tumors with normal gene dosage levels displayed a recurrent overexpression of UBE2C, S100A8, and CBX2, and downregulation of LOC389033, STC2, DNALI1, SCUBE2, NME5, SUSD3, SERPINA11, AZGP1, and PIP.