Visualizing global properties of a molecular dynamics trajectory.
Boston, United States. In Proteins, Jan 2016
Comparison of sigma-r plots calculated from 10 ns trajectories of proteins representing the four major SCOP fold classes indicates diversity of dynamic behaviors which are recognizably different among the four classes.
Improving Protein Fold Recognition by Deep Learning Networks.
Columbia, United States. In Sci Rep, 2014
We evaluated the performance of DN-Fold along with 18 different methods on Lindahl's benchmark dataset and on a large benchmark set extracted from SCOP 1.75 consisting of about one million protein pairs, at three different levels of fold recognition (i.e., protein family, superfamily, and fold) depending on the evolutionary distance between protein sequences.
SCOP/PHLPP and its functional role in the brain.
Tokyo, Japan. In Mol Biosyst, 2010
SCOP (suprachiasmatic nucleus (SCN) circadian oscillatory protein) was originally identified in 1999 in a differential display screen of the rat SCN for genes whose expression were regulated in a circadian manner (K.
SCOPing out proteases in long-term memory.
Belmont, United States. In Cell, 2007
In this issue, Shimizu et al. (2007) provide new insight into the regulation of this pathway by demonstrating that activation of MAP kinase occurs through the calcium-dependent degradation of SCOP (suprachiasmatic nucleus circadian oscillatory protein) by the protease calpain.