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Secretory carrier membrane protein 1

SCAMP1, SCAMP, Secretory Carrier Membrane Protein
This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, HAD, AGE, V1a, ACID
Papers using SCAMP1 antibodies
A dynamically regulated 14-3-3, Slob, and Slowpoke potassium channel complex in Drosophila presynaptic nerve terminals
Supplier
Nguyen Trung P. et al., In Journal of Neuroimmune Pharmacology, 1998
... SCAMP1 (22)BD Biosciences ...
Papers on SCAMP1
SCAMPs: A new tool for an old problem.
New
Rathod, Boston, United States. In J Hosp Med, Sep 2015
These data are then analyzed to change and improve the SCAMP algorithm itself.
Development of Standardized Clinical Assessment and Management Plans (SCAMPs) in Plastic and Reconstructive Surgery.
New
Greenberg et al., Boston, United States. In Plast Reconstr Surg Glob Open, Sep 2015
The SCAMP Champion, along with the SCAMPs support team, developed targeted data statements.
High Protein Intake Does Not Prevent Low Plasma Levels of Conditionally Essential Amino Acids in Very Preterm Infants Receiving Parenteral Nutrition.
New
Burgess et al., Liverpool, United Kingdom. In Jpen J Parenter Enteral Nutr, Aug 2015
BACKGROUND: We have shown that increasing protein intake using a standardized, concentrated, added macronutrients parenteral (SCAMP) nutrition regimen improves head growth in very preterm infants (VPIs) compared with a control parenteral nutrition (PN) regimen.
Concentrated parenteral nutrition solutions and central venous catheter complications in preterm infants.
New
Morgan et al., Liverpool, United Kingdom. In Arch Dis Child Fetal Neonatal Ed, May 2015
A PN regimen with increased macronutrient content (standardised, concentrated, added macronutrients parenteral (SCAMP)) has been shown to improve early head growth in a randomised controlled trial.
Commentary: Launch of a quality improvement network for evidence-based management of uncommon pediatric endocrine disorders: Turner syndrome as a prototype.
New
Rhodes et al., Farmington, United States. In J Clin Endocrinol Metab, Apr 2015
DESIGN: The first of the quality improvement programs to be implemented seeks to improve the care of 11- to 17-year-old girls with Turner syndrome who require initiation of estrogen replacement therapy by providing a standardized clinical assessment and management plan (SCAMP) for transdermal estradiol treatment to induce pubertal development.
Algorithms, clinical practice guidelines, and standardized clinical assessment and management plans: evidence-based patient management standards in evolution.
New
Stewart et al., Walnut Creek, United States. In Acad Med, Feb 2015
A care pathway, such as a SCAMP, includes multiple decision points and related recommendations.
Gathering and learning from relevant clinical data: a new framework.
New
Rathod et al., Boston, United States. In Acad Med, Feb 2015
A SCAMP is a care pathway, designed by clinicians, to guide medical decision making around a particular disorder.
Trans-Golgi network-located AP1 gamma adaptins mediate dileucine motif-directed vacuolar targeting in Arabidopsis.
Jiang et al., Hong Kong, Hong Kong. In Plant Cell, 2014
The dileucine motif also effectively rerouted the plasma membrane protein SCAMP1 to the tonoplast.
Earliest colonization events of Rhizophagus irregularis in rice roots occur preferentially in previously uncolonized cells.
Fujiwara et al., Tokyo, Japan. In Plant Cell Physiol, 2014
Here we observed that a green fluorescent protein (GFP)-tagged secretory carrier membrane protein (SCAMP) of rice was expressed even in cells with collapsed arbuscules, allowing live imaging coupled with GFP-SCAMP to evaluate the colonization and recolonization sequences.
Postnatal head growth in preterm infants: a randomized controlled parenteral nutrition study.
Turner et al., Liverpool, United Kingdom. In Pediatrics, 2014
We hypothesized that a Standardized, Concentrated With Added Macronutrients Parenteral (SCAMP) nutrition regimen would improve early head growth.
Traffic jam on the cellular secretory pathway generated by a replication protein from a plant RNA virus.
Okuno et al., Kyoto, Japan. In Plant Signal Behav, 2013
Here, we examined this possibility by using green fluorescent protein-fused rice SCAMP1 and Arabidopsis LRR84A as secretory pathway marker proteins and showed that p27 inhibited the trafficking of these proteins.
Secretory Carrier Membrane Protein (SCAMP) deficiency influences behavior of adult flies.
Numata et al., Vancouver, Canada. In Front Cell Dev Biol, 2013
Mammalian genomes contain five SCAMP genes SCAMP1-SCAMP5 that regulate membrane dynamics, most prominently membrane-depolarization and Ca(2+)-induced regulated secretion, a key mechanism for neuronal and neuroendocrine signaling.
Regulation of fusion pore closure and compound exocytosis in neuroendocrine PC12 cells by SCAMP1.
GeneRIF
Castle et al., Charlottesville, United States. In Traffic, 2011
Data suggest that SCAMP1's apparent dual role in facilitating dilation and closure of fusion pores implicates its function in exo-endocytic coupling and in the regulation of partial secretion.
Nonredundant function of secretory carrier membrane protein isoforms in dense core vesicle exocytosis.
GeneRIF
Castle et al., Charlottesville, United States. In Am J Physiol Cell Physiol, 2008
SCAMP isoforms regulate membrane fusion and dense core vesicle exocytosis in neurons.
Ubiquitously expressed secretory carrier membrane proteins (SCAMPs) 1-4 mark different pathways and exhibit limited constitutive trafficking to and from the cell surface.
GeneRIF
Castle et al., Charlottesville, United States. In J Cell Sci, 2005
SCAMPs travel between the cell surface and internal recycling systems, and form a mosaic with individual isoforms marking distinct pathways and functioning as trafficking machinery at sites of vesicle formation and fusion.
Tetraspan vesicle membrane proteins: synthesis, subcellular localization, and functional properties.
Review
Leube et al., Mainz, Germany. In Int Rev Cytol, 2001
In mammals synaptophysin, synaptoporin, pantophysin, and mitsugumin29 constitute the physins, synaptogyrin 1-4 the gyrins, and SCAMP1-5 the SCAMPs.
Scanning microphotolysis: three-dimensional diffusion measurement and optical single-transporter recording.
Review
Kubitscheck et al., M√ľnster, Germany. In Methods, 1999
Scanning microphotolysis (SCAMP) is a combination of fluorescence microphotolysis and confocal laser scanning microscopy.
Compartmentalization of protein traffic in insulin-sensitive cells.
Review
Pilch et al., Boston, United States. In Am J Physiol, 1996
Besides these proteins, which can be considered as vesicle "cargo", GLUT-4-containing vesicles have other components, like secretory carrier-associated membrane proteins (SCAMP), Rab(s), and vesicle-associated membrane protein (VAMP)/cellubrevin, which are ubiquitous to secretory vesicles and granules from different tissues.
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