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proteins. Page last changed on 19 Dec 2016.
Retinol dehydrogenase 11
The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity. [provided by RefSeq, Nov 2011] (from
Tani et al., Bangkok, Thailand. In Exp Hematol, May 2015
Lentivirally transduced UT-7/Epo erythroleukemic cells expressing ribosomal protein L11 (RPL11) or retinol dehydrogenase 11 (RDH11) could proliferate in the absence of erythropoietin, and their cell-cycle profiles revealed G0/G1 prolongation and low percentages of apoptosis.
Kasus-Jacobi et al., Oklahoma City, United States. In Invest Ophthalmol Vis Sci, 2008
Oxidative stress induced by exposure to constant bright light led to a rapid and significant decrease of RDH12 protein. The low and constant expression of RDH11 suggested a housekeeping function for this enzyme.
Edwards et al., Dallas, United States. In J Biol Chem, 2005
propose that mouse retinol dehydrogenase 11(mRDH11) disruption affects retinoid metabolism in photoreceptor inner segments and delays the kinetics of dark adaptation through modulation of calcium homeostasis