Papers on
SBP2
Orthostatic Blood Pressure Changes and Subclinical Markers of Atherosclerosis.Arita et al., Wakayama, Japan. In Am J Hypertens, Sep 2015
Stepwise regression analysis adjusted for age, sex, BMI, baseline SBP, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, fasting glucose, HbA1c, hs-CRP, IMT, late systolic peak of the pressure wave form (SBP2), and baPWV confirmed that baPWV, SBP2, and triglycerides were independently related to orthostatic BP changes.
Selective up-regulation of human selenoproteins in response to oxidative stress.Laurent et al., France. In Free Radic Biol Med, 2014
While a modest change in mRNA levels was noted, we identified a novel translational control mechanism stimulated by oxidative stress that is characterized by upregulation of UGA-selenocysteine recoding efficiency and relocalization of SBP2, EFsec and L30 recoding factors from cytoplasm to nucleus.
Inherited defects in thyroid hormone cell-membrane transport and metabolism.Dumitrescu et al., Chicago, United States. In Best Pract Res Clin Endocrinol Metab, 2014
Recessive mutations in the selenocysteine insertion sequence binding protein 2 (SBP2) gene present a variable clinical phenotype depending on the severity of the defect and its consequences on the selenoprotein hierarchy.
Inherited defects of thyroid hormone metabolism.Refetoff et al., Chicago, United States. In Ann Endocrinol (paris), 2011
Selenium (Se) is an essential trace element required for the biosynthesis of selenoproteins, and selenocysteine insertion sequence (SECIS) binding protein 2 (SBP2) represents a key trans-acting factor for the cotranslational insertion of selenocysteine into selenoproteins.
Mutations in SECISBP2 result in abnormal thyroid hormone metabolism.Refetoff et al., Chicago, United States. In Nat Genet, 2005
Systematic linkage analysis of genes involved in DIO2 synthesis and degradation led to the identification of an inherited Sec incorporation defect, caused by a homozygous missense mutation in SECISBP2 (also called SBP2).