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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Forkhead box Q1

satin, Foxq1, HFH-1, winged helix/forkhead transcription factor
FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).[supplied by OMIM, May 2009] (from NCBI)
Top mentioned proteins: CAN, HAD, ACID, OUT, HNF-3
Papers on satin
Thymoquinone alleviates nonalcoholic fatty liver disease in rats via suppression of oxidative stress, inflammation, apoptosis.
New
Sherief et al., Cairo, Egypt. In Naunyn Schmiedebergs Arch Pharmacol, Feb 2016
This model of 6 weeks high-fat high-cholesterol diet showed minimal fibrosis as noticed by increase MMP2 and Masson trichrome satin.
Gene expression profiling of prostate cancer-associated genes identifies fibromodulin as potential novel biomarker for prostate cancer.
New
Reyes et al., Cartagena, Colombia. In Int J Biol Markers, Jan 2016
Genes evaluated were ESM-1, SERPINE2, CLU, BGN, A2M, PENK, FMOD, CD81, DCN, TSPAN8, KBTBD10, F2RL1, TMSB4X, SNCG, CXXC5, FOXQ1, PDPN, SPN, CAV1, CD24 and KLK3.
FOXQ1 is overexpressed in laryngeal carcinoma and affects cell growth, cell cycle progression and cell invasion.
New
Guo et al., Shenyang, China. In Oncol Lett, Oct 2015
UNASSIGNED: Forkhead box Q1 (FOXQ1) is a forkhead transcription factor that is involved in numerous biological processes and has been shown to participate in tumorigenesis.
Identification of molecular determinants of primary and metastatic tumour re-initiation in breast cancer.
New
Impact
Tavazoie et al., New York City, United States. In Nat Cell Biol, May 2015
Tumorigenic-enriched subpopulations exhibited increased expression of LAMA4, FOXQ1 and NAP1L3—genes that are also expressed at greater levels by independently derived metastatic subpopulations.
Prior infection with Type A Francisella tularensis antagonizes the pulmonary transcriptional response to an aerosolized Toll-like receptor 4 agonist.
Ozinsky et al., Seattle, United States. In Bmc Genomics, 2014
Analysis of the promotors of LPS-responsive genes that were perturbed by Type A Francisella infection identified candidate transcription factors that were potentially modulated by the bacteria, including multiple members of the forkhead transcription factor family (FoxA1, Foxa2, FoxD1, Foxd3, Foxf2, FoxI1, Fox03, Foxq1), IRF1, CEBPA, and Mef2.
Genome-Wide Screening of mRNA Expression in Leprosy Patients.
Soares et al., São Paulo, Brazil. In Front Genet, 2014
Some of these genes were observed in all forms of the disease (CD2, CD27, chit1, FA2H, FAM26F, GZMB, MMP9, SLAMF7, UBD) and others were exclusive to reactional forms (Type "1" reaction: GPNMB, IL1B, MICAL2, FOXQ1; Type "2" reaction: AKR1B10, FAM180B, FOXQ1, NNMT, NR1D1, PTX3, TNFRSF25).
Novel monocyte biomarkers of atherogenic conditions.
Review
Kzhyshkowska et al., Mannheim, Germany. In Curr Pharm Des, 2012
These include stabilin-1, FOXQ1 and IL17RB.
Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function.
GeneRIF
Andreassen et al., Oslo, Norway. In J Psychiatr Res, 2012
this study showed that an interaction between FOXQ1 and SUMO1P1 for psychomotor speed.
FOXQ1 regulates epithelial-mesenchymal transition in human cancers.
GeneRIF
Yu et al., Singapore, Singapore. In Cancer Res, 2011
Mechanistic investigations revealed that FOXQ1-induced EMT was associated with transcriptional inactivation of the epithelial regulator E-cadherin. Findings define a key role for FOXQ1 in regulating EMT and aggressiveness in human cancer.
The Forkhead factor FoxQ1 influences epithelial differentiation.
GeneRIF
Gröne et al., Heidelberg, Germany. In J Cell Physiol, 2011
This study has elucidated the functional impact of FoxQ1 on epithelial differentiation.
Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis.
GeneRIF
Wu et al., Detroit, United States. In Cancer Res, 2011
Foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis.
Ezetimibe as a potential treatment for dyslipidemia associated with chronic renal failure and renal transplant.
Review
Khalil et al., Middlesbrough, United Kingdom. In Saudi J Kidney Dis Transpl, 2010
The current evidence suggests that the addition of ezetimibe to satin is effective and safe in treating dyslipidemia in the CKD and the kidney transplant patients.
FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth.
GeneRIF
Nishio et al., Ōsaka, Japan. In Cancer Res, 2010
FOXQ1 overexpression upregulated several genes that have positive roles for tumor growth of colorectal cancer.
VEGF inhibitors and vitrectomy for diabetic vitreoretinopathy.
Review
Farah et al., São Paulo, Brazil. In Dev Ophthalmol, 2008
A better visualization of remaining cortex vitreous or adjacent epiretinal membrane and safer removal may be achieved by a better intraoperative visualization using a variety of vital dyes to satin retinal tissue (chromovitrectomy).
Subtelomeric deletions of chromosome 6p: molecular and cytogenetic characterization of three new cases with phenotypic overlap with Ritscher-Schinzel (3C) syndrome.
Review
Krantz et al., Philadelphia, United States. In Am J Med Genet A, 2005
Three forkhead genes (FOXF1 and FOXQ1 from within the critical region, and FOXC1 proximal to this region) were evaluated as potential candidate disease genes for this disorder.
Forkhead transcription factors in immunology.
Review
Peng et al., Saint Louis, United States. In Cell Mol Life Sci, 2005
Roles for other forkhead genes have also been proposed, including Foxp1 in macrophage differentiation, Foxq1 in natural killer cell effector function and Foxd2 in T cell activation.
Variable female preferences drive complex male displays.
Impact
Borgia et al., College Park, United States. In Nature, 2004
Here we show that in satin bowerbirds (Ptilonorhynchus violaceus) female mate choice is a multistage process, where females of different ages use different male display traits in successive stages.
Male displays adjusted to female's response.
Impact
Borgia et al., College Park, United States. In Nature, 2002
Here we use robotic females in a field experiment to demonstrate that male satin bowerbirds (Ptilonorhynchus violaceus) do not always display at maximum intensity - rather, successful males modulate their displays in response to signals from females.
FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance.
Impact
Enerbäck et al., Göteborg, Sweden. In Cell, 2001
We have identified the human winged helix/forkhead transcription factor gene FOXC2 as a key regulator of adipocyte metabolism.
The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome.
Impact
Pilia et al., Cagliari, Italy. In Nat Genet, 2001
We have positionally cloned a novel, putative winged helix/forkhead transcription factor gene, FOXL2, that is mutated to produce truncated proteins in type I families and larger proteins in type II.
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