Autolytic transition of mu-calpain upon activation as resolved by antibodies distinguishing between the pre- and post-autolysis forms.
In PLoS ONE, 1991
... (1∶500, DAKO, Carpinteria, CA), rabbit anti-Synapsin I (1∶500, Millipore), mouse anti-Cux1 (1∶100, Abnova, Taipei, Taiwan), rabbit anti-Satb2 (1∶1000, Abcam, Cambridge, UK), rat anti-Ctip2 ...
SATB1 and 2 in colorectal cancer.
New York City, United States. In Carcinogenesis, Feb 2015
Expression of the SATB2 gene is tissue-specific, and the only epithelial cells expressing SATB2 are the glandular cells of the lower gastrointestinal tract where its expression is regulated by microRNA-31 (miR-31) and miR-182.
The role of SATB2 in skeletogenesis and human disease.
Shanghai, China. In Cytokine Growth Factor Rev, 2014
Since the discovery of SATB2 (special AT-rich sequence binding protein 2) a decade ago, its pivotal roles in development and tissue regeneration have emerged, particularly in craniofacial patterning and development, palate formation, and osteoblast differentiation and maturation.
Sequencing chromosomal abnormalities reveals neurodevelopmental loci that confer risk across diagnostic boundaries.
Boston, United States. In Cell, 2012
We sequenced BCAs in patients with autism or related NDDs, revealing disruption of 33 loci in four general categories: (1) genes previously associated with abnormal neurodevelopment (e.g., AUTS2, FOXP1, and CDKL5), (2) single-gene contributors to microdeletion syndromes (MBD5, SATB2, EHMT1, and SNURF-SNRPN), (3) novel risk loci (e.g., CHD8, KIRREL3, and ZNF507), and (4) genes associated with later-onset psychiatric disorders (e.g., TCF4, ZNF804A, PDE10A, GRIN2B, and ANK3).
Epitope mapping of antibodies using bacterial surface display.
Stockholm, Sweden. In Nat Methods, 2008
We analyzed the binding sites of both monoclonal and polyclonal antibodies directed to three human protein targets: (i) the human epidermal growth factor receptor 2 (HER2), (ii) ephrin-B3 and (iii) the transcription factor SATB2.
Bone formation: The nuclear matrix reloaded.
Kansas City, United States. In Cell, 2006
In this issue of Cell, Grosschedl and colleagues (Dobreva et al., 2006) report that the nuclear matrix protein Satb2 represses Hoxa2 expression and acts with other regulatory proteins to promote osteoblast differentiation.