Germline mutations causing familial lung cancer.
Nagasaki, Japan. In J Hum Genet, Oct 2015
We detected somatic 'candidate' mutations in multiple sporadic lung cancer samples; MAST1, CENPE, CACNB2 and LCT were the most promising candidate genes.
Epitope Fingerprinting for Recognition of the Polyclonal Serum Autoantibodies of Alzheimer's Disease.
Uberlândia, Brazil. In Biomed Res Int, 2014
The putative antigens MAST1, Enah, MAO-A, X11/MINT1, HGF, SNX14, ARHGAP 11A, APC, and CENTG3, which have been associated with AD or have functions in neural tissue, may indicate possible therapeutic targets.
[Fibrinolysis in acute CVA: the current status].
Coimbra, Portugal. In Acta Med Port, 1997
All three studies with Estreptoquinase--MAST-E, MAST-I and ASK--ended prematurely due to the high rates of mortality and intracranial haemorrhage observed in the group of patients treated with this drug.
Thrombolytic therapy in the treatment of stroke.
Los Angeles, United States. In Drugs, 1996
The Multicentre Acute Stroke Trial-Europe (MAST-E), the Australia Streptokinase (ASK), and the Multicentre Acute Stroke Trial-Italy (MAST-I) trials, which evaluated intravenous streptokinase 1.5 x 10(6) IU in patients with acute ischaemic stroke, were terminated prematurely because of excessive early mortality and symptomatic intracranial haemorrhage in streptokinase recipients compared with those treated with placebo.