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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

SAM and SH3 domain containing 1

SASH1, SAM and SH3 domain containing 1
Top mentioned proteins: iMpact, SLY1, CAN, HAD, PCNA
Papers on SASH1
Genome-wide association study for rotator cuff tears identifies two significant single-nucleotide polymorphisms.
New
Teerlink et al., Salt Lake City, United States. In J Shoulder Elbow Surg, Feb 2016
RESULTS: Tests of association revealed 2 significantly associated SNPs, one occurring in SAP30BP (rs820218; P = 3.8E-9) on chromosome 17q25 and another occurring in SASH1 (rs12527089; P = 1.9E-7) on chromosome 6q24.
Identification of gene expression signature for cigarette smoke exposure response-from man to mouse.
New
Peitsch et al., Neuchâtel, Switzerland. In Hum Exp Toxicol, Dec 2015
The signature consisted of LRRN3, SASH1, PALLD, RGL1, TNFRSF17, CDKN1C, IGJ, RRM2, ID3, SERPING1, and FUCA1.
SASH1, a new potential link between smoking and atherosclerosis.
New
Ninio et al., Paris, France. In Atherosclerosis, Oct 2015
OBJECTIVE: We have previously reported that SASH1 expression is increased in circulating human monocytes from smokers and was positively correlated with the number of carotid atherosclerotic plaques.
Influence of Smoking Status and Intensity on Discovery of Blood Pressure Loci Through Gene-Smoking Interactions.
New
Rao et al., Boston, United States. In Genet Epidemiol, Sep 2015
Associations of loci near SASH1 and KLHL6/KLHL24 with SBP may be modulated by tobacco smoking.
Autosomal-recessive SASH1 variants associated with a new genodermatosis with pigmentation defects, palmoplantar keratoderma and skin carcinoma.
New
Faivre et al., Dijon, France. In Eur J Hum Genet, Jul 2015
SASH1 (SAM and SH3 domain-containing protein 1) is a tumor suppressor gene involved in the tumorigenesis of a spectrum of solid cancers.
Clinical Significance of SASH1 Expression in Glioma.
Liu et al., Nantong, China. In Dis Markers, 2014
OBJECTIVE: SAM and SH3 domain containing 1 (SASH1) is a recently discovered tumor suppressor gene.
Gene expression profiling of pre-eclamptic placentae by RNA sequencing.
FINNPEC Core Investigator Group et al., Helsinki, Finland. In Sci Rep, 2014
Some of the genes identified in our study have been reported by numerous microarray studies (BHLHE40, FSTL3, HK2, HTRA4, LEP, PVRL4, SASH1, SIGLEC6), but many have been implicated in only few studies or have not previously been linked to pre-eclampsia (ARMS2, BTNL9, CCSAP, DIO2, FER1L4, HPSE, LOC100129345, LYN, MYO7B, NCMAP, NDRG1, NRIP1, PLIN2, SBSPON, SERPINB9, SH3BP5, TET3, TPBG, ZNF175).
SASH1 inhibits proliferation and invasion of thyroid cancer cells through PI3K/Akt signaling pathway.
Zhang et al., Qingdao, China. In Int J Clin Exp Pathol, 2014
The SASH1 (SAM- and SH3-domain containing 1) gene, a member of the SLY-family of signal adapter proteins, has an important regulatory role in tumorigenesis, but its implication in thyroid carcinoma has not been yet investigated.
Promoter methylation assay of SASH1 gene in hepatocellular carcinoma.
Liren et al., Nantong, China. In J Buon, 2014
PURPOSE: To analyse the relationship between the expression of SASH1 and its methylation level in human hepatocellular carcinoma.
A genome-wide association study to identify genomic modulators of rate control therapy in patients with atrial fibrillation.
Darbar et al., Yokohama, Japan. In Am J Cardiol, 2014
These included 6q24.3 (near SAMD5/SASH1, p = 9.36 × 10(-8)), 4q12 (IGFBP7, p = 1.75 × 10(-7)), 6q22.33 (C6orf174, p = 4.86 × 10(-7)), 3p21.31
IgA measurements in over 12 000 Swedish twins reveal sex differential heritability and regulatory locus near CD30L.
Magnusson et al., Stockholm, Sweden. In Hum Mol Genet, 2014
The genome-wide association study revealed significant association to two loci: (i) rs6928791 located on chromosome 6, 22 kb upstream of the gene SAM and SH3 domain containing 1 (SASH1) and (ii) rs13300483 on chromosome 9, situated 12 kb downstream the CD30 ligand (CD30L) encoding gene.
Protein and siRNA delivery by transportan and transportan 10 into colorectal cancer cell lines.
Kmiec et al., Gdańsk, Poland. In Folia Histochem Cytobiol, 2013
The uptake of streptavidin-FITC complex into cells was determined by flow cytometry and fluorescence microscopy, with the inhibition of cellular vesicle trafficking by brefeldin A. The efficiency of siRNA for SASH1 gene delivery was measured by quantitative PCR (qPCR).
Promoter methylation assay of SASH1 gene in breast cancer.
Lin et al., Shanghai, China. In J Buon, 2013
PURPOSE: To analyze the relationship between the expression of SASH1 and its methylation level of SASH1 gene promoter in human breast cancer.
SASH1 is a scaffold molecule in endothelial TLR4 signaling.
Karsan et al., Vancouver, Canada. In J Immunol, 2013
In this study, we identify a novel scaffold protein in TLR4 signaling called SAM and SH3 domain containing protein 1 (SASH1).
Research resource: preovulatory LH surge effects on follicular theca and granulosa transcriptomes.
Vanselow et al., Kansas City, United States. In Mol Endocrinol, 2013
Minimal expression differences were observed between aGCs and mGCs; however, transcripts encoding extracellular proteins (NID2) and matrix modulators (ADAMTS1, SASH1) dominated these differences.
The candidate tumor suppressor SASH1 interacts with the actin cytoskeleton and stimulates cell-matrix adhesion.
GeneRIF
Janssen et al., München, Germany. In Int J Biochem Cell Biol, 2011
A mechanistic role for SASH1 in tumor formation by regulating the adhesive and migratory behavior of cancer cells has been shown.
Prognostic significance of downregulated expression of the candidate tumour suppressor gene SASH1 in colon cancer.
GeneRIF
Janssen et al., München, Germany. In Br J Cancer, 2006
Downregulated expression of the candidate tumour suppressor gene SASH1 is associated with colon cancer
Differential expression and molecular characterisation of Lmo7, Myo1e, Sash1, and Mcoln2 genes in Btk-defective B-cells.
GeneRIF
Smith et al., Huddinge, Sweden. In Cell Immunol, 2005
Not expressed in the investigated haematopoietic cell lines, while transcripts were found in whole splenic B-cells from both wild type and Btk-defective mice.
SASH1: a candidate tumor suppressor gene on chromosome 6q24.3 is downregulated in breast cancer.
GeneRIF
Scherneck et al., Berlin, Germany. In Oncogene, 2003
tumor suppressor gene possibly involved in tumorigenesis of breast and other solid cancers
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