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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Protein phosphatase 6, regulatory subunit 2

SAPS2, PP6R2
Protein phosphatase regulatory subunits, such as SAPS2, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS2 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010] (from NCBI)
Top mentioned proteins: LNP, Saps, HAD, AGE, PP6
Papers on SAPS2
Trace element monitoring in the ICU: quality and economic impact of a change in sampling practice.
New
Berger et al., Lausanne, Switzerland. In Clin Nutr, Jun 2015
The 2009 patients had higher SAPS2 scores (p = 0.02) and lower BMI compared to 2006 (p = 0.007).
Use of aztreonam in association with cefepime for the treatment of nosocomial infections due to multidrug-resistant strains of Pseudomonas aeruginosa to β-lactams in ICU patients: A pilot study.
New
Mahjoub et al., Amiens, France. In Anaesth Crit Care Pain Med, Jun 2015
The median [25th-75th percentiles] admission SAPS2 score was 54 [51-69] and the median SOFA score at the beginning of infection was 7 [4-8].
Evaluation of endothelial biomarkers as predictors of organ failures in septic shock patients.
New
Mathieu et al., Lille, France. In Cytokine, Jun 2015
RESULTS: Significant correlations were found between angiopoietin-2 and severity scores at Day 1: SAPS2 (r(2)=0.620;
Epidemiology of filamentous fungal infections in burned patients: A French retrospective study.
New
Bargues et al., Clamart, France. In Burns, Jun 2015
Total body surface area burned, full-thickness burn surface area, Unit Burn Standard, Tobiasen score and SAPS2 (respectively 55% [40-73], 45% [30-63], 180 [129-259], 11 [8-12] and 50 [40-62]) were markedly higher than in burned patients without FFI hospitalised during the same time period.
Impact of imipenem and amikacin pharmacokinetic/pharmacodynamic parameters on microbiological outcome of Gram-negative bacilli ventilator-associated pneumonia.
New
Wolff et al., Paris, France. In J Antimicrob Chemother, May 2015
RESULTS: Thirty-nine patients [median (min-max) age = 60 years (28-84) and median SAPS2 at inclusion = 40 (19-73)] were included.
Stress (Tako-tsubo) cardiomyopathy in critically-ill patients.
New
Lefort et al., Tours, France. In Eur Heart J Acute Cardiovasc Care, Apr 2015
SAPS2, renal impairment, malnutrition, norepinephrine infusion and thrombocytopenia were associated with death in the univariate analysis.
Persistently elevated osteopontin serum levels predict mortality in critically ill patients.
Luedde et al., Aachen, Germany. In Crit Care, 2014
However, persistently elevated OPN levels at day 3 of ICU treatment were a strong independent predictor for an unfavorable prognosis, with similar or better diagnostic accuracy than routinely used markers of organ failure or prognostic scoring systems such as SAPS2 or APACHE II score.
Risk Factors for Acute Kidney Injury and In-Hospital Mortality in Patients Receiving Extracorporeal Membrane Oxygenation.
Na et al., South Korea. In Plos One, 2014
The simplified acute physiology score 2 (SAPS2) and serum sodium level were also associated with in-hospital mortality, with HRs of 1.02 (1.004-1.035)
SAPS 3 is not superior to SAPS 2 in cardiac surgery patients.
Hekmat et al., In Scand Cardiovasc J, 2014
OBJECTIVES: Cardiac surgery patients are excluded from SAPS2 but included in SAPS3.
Measurement of endotracheal tube secretions volume by micro computed tomography (MicroCT) scan: an experimental and clinical study.
Pesenti et al., Monza, Italy. In Bmc Anesthesiol, 2013
The amount of secretions inversely correlated with patients' age (p = 0.011, rho = -0.727) but not with days of intubation, SAPS2, PaO2/FiO2 assessed on admission.
Determinants of noninvasive ventilation success or failure in morbidly obese patients in acute respiratory failure.
Mallat et al., Lens, France. In Plos One, 2013
Factors associated with NIV failure included pneumonia (n = 12/13, 92% vs n = 9/63, 14%; p<0.0001), high SOFA (10 vs 5; p<0.0001) and SAPS2 score (63 vs 39; p<0.0001) at admission.
Ultrasound-guided central venous cannulation is superior to quick-look ultrasound and landmark methods among inexperienced operators: a prospective randomized study.
Slama et al., Amiens, France. In Intensive Care Med, 2013
The mean age of patients included in the study was 65 ± 15 years, and the mean Simplified Acute Physiology Score 2 (SAPS2) was 57 ± 20.
Clinical accuracy of RIFLE and Acute Kidney Injury Network (AKIN) criteria for predicting hospital mortality in critically ill patients with multi-organ dysfunction syndrome.
Hantaweepant et al., Bangkok, Thailand. In J Med Assoc Thai, 2013
The APACHE II had the best discriminative accuracy for mortality (AUC = 0.80), followed by the SAPS3 scores (AUC = 0.77) and SAPS2 (AUC = 0.76).
The prognostic value of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13) deficiency in septic shock patients involves interleukin-6 and is not dependent on disseminated intravascular coagulation.
Veyradier et al., In Crit Care, 2012
By multivariate analysis, Simplified Acute Physiology Score 2 (SAPS2) score (odds ratio (OR) 1.11/point; 95% CI 1.01 to 1.24) and ADAMTS13 activity <30% (OR 11.86; 95% CI 1.36 to 103.52) were independently associated with hospital mortality.
Pentraxin-3 serum levels are associated with disease severity and mortality in patients with systemic inflammatory response syndrome.
Garred et al., Copenhagen, Denmark. In Plos One, 2012
The serum levels of PTX3 correlated significantly with SAPS2 score (Spearman's rho 0.28, p<0.0001).
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