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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

RSE1 Rse1p

SAP130, Rse1p, RSE1, involved in ER-to-Golgi transport
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Histone, fibrillin-1, CAN, Mincle, C-1
Papers on SAP130
Redox-dependent disulfide bond formation in SAP30L corepressor protein: Implications for structure and function.
New
Jänis et al., Joensuu, Finland. In Protein Sci, Dec 2015
UNASSIGNED: Sin3A-associated protein 30-like (SAP30L) is one of the key proteins in a multi-subunit protein complex involved in transcriptional regulation via histone deacetylation.
Macrophage-Inducible C-Type Lectin/Spleen Tyrosine Kinase Signaling Pathway Contributes to Neuroinflammation After Subarachnoid Hemorrhage in Rats.
New
Zhang et al., Hangzhou, China. In Stroke, Aug 2015
Mincle small interfering RNA, recombinant SAP130, and a selective Syk phosphorylation inhibitor piceatannol were used for intervention.
Mincle signaling in the innate immune response after traumatic brain injury.
New
de Rivero Vaccari et al., New Orleans, United States. In J Neurotrauma, Mar 2015
Here we report that mincle is activated by SAP130 in cortical neurons in culture, resulting in production of the inflammatory cytokine TNF.
Mincle, an Innate Immune Receptor, Is Expressed in Urothelial Cancer Cells of Papillomavirus-Associated Urothelial Tumors of Cattle.
Roperto et al., Napoli, Italy. In Plos One, 2014
Furthermore it senses dead cells through its primary ligand SAP130.
Cyclodextrin inclusion complex of racecadotril: effect of drug-β- cyclodextrin ratio and the method of complexation.
Semalty et al., Srīnagar, India. In Curr Drug Discov Technol, 2014
Complex prepared by solvent evaporation method (RSE1:1, RSE1:2) were found to be showing irregular disc shaped non-porous surface, while the complexes prepared by kneading method (RK1:1, RK1:2) showed rough, fluffy, non-porous and irregular surface in SEM.
Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population.
Guerrero-Preston et al., Baltimore, United States. In Epigenetics, 2014
Bioinformatics analysis revealed GGTLA4, FKBP6, ZNF516, SAP130, and INTS1 to be differentially methylated in cancer and normal tissues in the Discovery cohort.
Proteins associated with SF3a60 in T. brucei.
Levin et al., Buenos Aires, Argentina. In Plos One, 2013
The interactions with SF3a120, SF3a66 and SAP130 were confirmed by tandem affinity purification and mass spectrometry.
Regulation of Cullin-RING ubiquitin ligase 1 by Spliceosome-associated protein 130 (SAP130).
Hagen et al., Singapore, Singapore. In Biol Open, 2013
It has been reported that the Spliceosome-associated protein 130 (SAP130/SF3b-3) binds to several Cullin proteins, yet it remains unknown whether SAP130 plays any role in regulating the function of CRLs.
Calibration and field test of the Polar Organic Chemical Integrative Samplers for the determination of 15 endocrine disrupting compounds in wastewater and river water with special focus on performance reference compounds (PRC).
Paschke et al., Bilbao, Spain. In Water Res, 2013
Using the continuous-flow calibration device, lab-based sampling rates were determined for all the target compounds (RSBPA = 0.0326 L/d; RScisADT = 0.0800 L/d, RSE1 = 0.0398 L/d, RSEQ = 0.0516 L/d, RSTT = 0.0745 L/d, RSE2 = 0.0585 L/d, RSEE2 = 0.0406 L/d, RSNT = 0.0846 L/d, RSPG = 0.0478 L/d and RSE3 = 0.1468 L/d), except for DES, MeEE2, 4tOP, 4OP, 4NPs, where the uptake after 14 days POCIS exposure was found to be insignificant or indicated a no linear behaviour.
Involvement of Mincle and Syk in the changes to innate immunity after ischemic stroke.
Hara et al., Gifu, Japan. In Sci Rep, 2012
In the present study, we showed that Mincle, its ligand SAP130, and its downstream phospho-Syk/Syk were upregulated after ischemia, and that Mincle is expressed in immune and non-immune cells in the ischemic brains of mice and human.
SAP155-mediated splicing of FUSE-binding protein-interacting repressor serves as a molecular switch for c-myc gene expression.
Nomura et al., Chiba, Japan. In Mol Cancer Res, 2012
FIR, SAP155, SAP130, and c-myc were coordinately upregulated in human colorectal cancer.
DRBD1 is the Trypanosoma brucei homologue of the spliceosome-associated protein 49.
Clayton et al., Heidelberg, Germany. In Mol Biochem Parasitol, 2009
In mammalian cells and yeast, U2 snRNP is associated with the multimeric factor SF3b, which contains p14, SF3b10, SF3b14b, SAP49, SAP130, SAP145 and SAP155.
A mutation in teg-4, which encodes a protein homologous to the SAP130 pre-mRNA splicing factor, disrupts the balance between proliferation and differentiation in the C. elegans germ line.
Hansen et al., Calgary, Canada. In Mech Dev, 2009
Dividing stem cells can give rise to two types of daughter cells; self-renewing cells that have virtually the same properties as the parent cell, and differentiating cells that will eventually form part of a tissue.
Silencing of the transforming growth factor-beta (TGFbeta) receptor II by Kruppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFbeta signaling.
GeneRIF
Urrutia et al., Rochester, United States. In J Biol Chem, 2009
the TGFbeta pathway activation leads to recruitment of a KLF14-mSin3A-HDAC2 repressor complex to the TGFbetaRII promoter, as well as the remodeling of chromatin to increase histone marks that associate with transcriptional silencing.
Mincle is an ITAM-coupled activating receptor that senses damaged cells.
Impact
Saito et al., Yokohama, Japan. In Nat Immunol, 2008
Mincle-expressing cells were activated in the presence of dead cells, and we identified SAP130, a component of small nuclear ribonucloprotein, as a Mincle ligand that is released from dead cells.
Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome.
Wei et al., New Haven, United States. In Bmc Biochem, 2007
RESULTS: We report isolation of SAP130 (SF3b-3) as a CSN1 interacting protein.
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