Lipin-1 and lipin-3 together determine adiposity in vivo.
Los Angeles, United States. In Mol Metab, 30 Apr 2014
Analysis of PAP activity in additional metabolic tissues from lipin single- and double-knockout mice also revealed roles for lipin-1 and lipin-3 in spleen, kidney, and liver, for lipin-1 alone in heart and skeletal muscle, and for lipin-1 and lipin-2 in lung and brain.
Assessment of biomarkers and predictive model for short-term prospective abdominal aortic aneurysm growth - a pilot study.
Madrid, Spain. In Ann Vasc Surg, 10 Apr 2014
We registered: clinical data (age, gender, cardiovascular risk factors, comorbidity, statin intake), baseline aortic diameter, prospective 1-year AAA growth, and the concentration of metalloprotease-2, metalloprotease-9, cystatin C, alpha1-antitrypsin, myeloperoxidase, monocyte chemoattractant protein-1, homocystein, D-dimer, plasmin-antiplasmin complex (PAP) and C-reactive protein in peripheral blood at the time of baseline assessment.
Molecular diagnosis of prostate cancer: are we up to age?
Philadelphia, United States. In Semin Oncol, Jun 2013
Historically used biomarkers such as prostatic acid phosphatase (PAP), serum prostate-specific antigen (PSA), and its precursor have not stood the challenge of sensitivity and specificity.
Emerging Roles of Human Prostatic Acid Phosphatase.
South Korea. In Biomol Ther (seoul), 2013
Prostatic acid phosphatase (PAP) is a non-specific phosphomonoesterase synthesized in prostate epithelial cells and its level proportionally increases with prostate cancer progression.
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs.
More papers using
Madison, United States. In Nature, 2008
Here we show that PIPKIalpha co-localizes at nuclear speckles and interacts with a newly identified non-canonical poly(A) polymerase, which we have termed Star-PAP (nuclear speckle targeted PIPKIalpha regulated-poly(A) polymerase) and that the activity of Star-PAP can be specifically regulated by PtdIns4,5P2.