Molecular targets and pathways involved in liver metastasis of colorectal cancer.
München, Germany. In Clin Exp Metastasis, Aug 2015
In addition, the functional role and validation of targets such as PRL3, Trop-2, L1CAM, S100A4, S100P, CD133, LIPC, and APOBEC3G are summarized.
L1CAM in human cancer.
Mannheim, Germany. In Int J Cancer, Jul 2015
UNASSIGNED: L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system.
Serpins promote cancer cell survival and vascular co-option in brain metastasis.
New York City, United States. In Cell, 2014
Plasmin suppresses brain metastasis in two ways: by converting membrane-bound astrocytic FasL into a paracrine death signal for cancer cells, and by inactivating the axon pathfinding molecule L1CAM, which metastatic cells express for spreading along brain capillaries and for metastatic outgrowth.