Molecular targets and pathways involved in liver metastasis of colorectal cancer.
München, Germany. In Clin Exp Metastasis, Aug 2015
In addition, the functional role and validation of targets such as PRL3, Trop-2, L1CAM, S100A4, S100P, CD133, LIPC, and APOBEC3G are summarized.
L1CAM in human cancer.
Mannheim, Germany. In Int J Cancer, Jul 2015
UNASSIGNED: L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system.
MECP2 duplication syndrome in a Chinese family.
Beijing, China. In Bmc Med Genet, 2014
The duplication segment which was detected by multiplex ligation-dependent probe amplification (MLPA) included gene MECP2, interleukin-1 receptor-associated kinase 1 (IRAK1), filamin A (FLNA), and L1 cell adhesion molecule (L1CAM).
Serpins promote cancer cell survival and vascular co-option in brain metastasis.
New York City, United States. In Cell, 2014
Plasmin suppresses brain metastasis in two ways: by converting membrane-bound astrocytic FasL into a paracrine death signal for cancer cells, and by inactivating the axon pathfinding molecule L1CAM, which metastatic cells express for spreading along brain capillaries and for metastatic outgrowth.