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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Retinoid X receptor, gamma

RXRG, retinoid X receptor gamma
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010] (from NCBI)
Top mentioned proteins: ACID, retinoid X receptor alpha, CAN, Insulin, V1a
Papers on RXRG
Ectopic cross-talk between thyroid and retinoic acid signaling: A possible etiology for spinal neural tube defects.
Zhang et al., Beijing, China. In Gene, Jan 2016
The promoters of the RA signaling genes CRABP1 and RARB were ectopically occupied by increased RXRG and RXRB but displayed decreased levels of inhibitory histone modifications, suggesting that elevated TH signaling abnormally stimulates RA signaling genes.
Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor.
Ghyselinck et al., Illkirch-Graffenstaden, France. In Plos Genet, Oct 2015
To address this question, we have analyzed the phenotypes of mice lacking, in spermatogonia, all rexinoid receptors (RXRA, RXRB and RXRG) or all ATRA receptors (RARA, RARB and RARG).
Regulation of retinoid X receptor gamma expression by fed state in mouse liver.
Kim et al., Kangnŭng, South Korea. In Biochem Biophys Res Commun, Mar 2015
Glucose metabolism is balanced by glycolysis and gluconeogenesis with precise control in the liver.
Peroxisome proliferator activator receptor gamma (PPARG) regulates conceptus elongation in sheep.
Spencer et al., Pullman, United States. In Biol Reprod, Feb 2015
Expression of PPARD, PPARG, RXRA, RXRB, and RXRG is detected in the elongating ovine conceptus, and nuclear PPARD and PPARG are present in the trophectoderm.
Comparison of microarray expression profiles between follicular variant of papillary thyroid carcinomas and follicular adenomas of the thyroid.
Al-Maghrabi et al., In Bmc Genomics, 2014
Amongst the most significantly upregulated genes in FVPTCs were GABA B receptor, 2 (GABBR2), neuronal cell adhesion molecule (NRCAM), extracellular matrix protein 1 (ECM1), heparan sulfate 6-O-sulfotransferase 2 (HS6ST2), and retinoid X receptor, gamma (RXRG).
Obestatin and Nt8U influence glycerolipid metabolism and PPAR gamma signaling in mice.
Manjappara et al., Mysore, India. In Int J Biochem Cell Biol, 2014
It also upregulated peroxisome proliferator-activated receptor gamma, retinoid X receptor gamma, cluster of differentiation 36, adiponectin, C1Q and collagen domain containing, angiopoietin-like 4, lipoprotein lipase, stearoyl-coenzyme A and desaturase 3 involved in the peroxisome proliferator-activated receptor signaling pathway.
Counterphase modulation flicker photometry: phenotypic and genotypic associations.
Mollon et al., In J Opt Soc Am A Opt Image Sci Vis, 2014
This marker is close to the gene RXRG, which encodes a nuclear receptor, retinoid X receptor γ.
Dietary energy source largely affects tissue fatty acid composition but has minor influence on gene transcription in Iberian pigs.
López-Bote et al., Madrid, Spain. In J Anim Sci, 2014
Quantitative PCR confirmed several DE genes in adipose tissue (RXRG, LEP, and ME1; P < 0.0001, P < 0.05, and P < 0.0001, respectively), but no DE gene was found in loin or liver tissues.
Interaction between allelic variations in vitamin D receptor and retinoid X receptor genes on metabolic traits.
Hyppönen et al., London, United Kingdom. In Bmc Genet, 2013
The biological actions of 1, 25-dihydroxyvitamin D, are mediated through the vitamin D receptor (VDR), which heterodimerizes with retinoid X receptor, gamma (RXRG).
Association of RXR-Gamma Gene Variants with Familial Combined Hyperlipidemia: Genotype and Haplotype Analysis.
Baroni et al., Roma, Italy. In J Lipids, 2012
This region includes the retinoid X receptor gamma (RXRG), a nuclear factor member of the RXR superfamily, which plays important roles in lipid homeostasis.
Genome wide association study of age at menarche in the Japanese population.
Matsuda et al., Tokyo, Japan. In Plos One, 2012
In addition, six loci in or near CCDC85A, LOC100421670, CA10, ZNF483, ARNTL, and RXRG exhibited suggestive association with AAM (P<0.05).
Early induction of cytokines/cytokine receptors and Cox2, and activation of NF-κB in 4-nitroquinoline 1-oxide-induced murine oral cancer model.
Chung et al., Taiwan. In Toxicol Appl Pharmacol, 2012
MetaCore analysis revealed the most striking metabolic alterations in tumor tissues, especially in lipid metabolism resulting from the reduction of Pparα and Rxrg.
Retinoid receptors trigger neuritogenesis in retinal degenerations.
Marc et al., Salt Lake City, United States. In Faseb J, 2012
Using the light-induced retinal degeneration (LIRD) mouse model, which provides a unique platform for exploring the mechanisms underlying neuritogenesis, we found that retinoid X receptors (RXRs) control neuritogenesis.
The arthritis severity locus Cia5a regulates the expression of inflammatory mediators including Syk pathway genes and proteases in pristane-induced arthritis.
Gulko et al., United States. In Bmc Genomics, 2011
Nuclear receptors (NR) such as Rxrg, Pparg and Rev-erba were increased in the protected congenics, and so was the anti-inflammatory NR-target gene Scd1 (54-fold increase).
Retinoid X receptor gamma signaling accelerates CNS remyelination.
Franklin et al., Cambridge, United Kingdom. In Nat Neurosci, 2011
results indicate that RXR-gamma is a positive regulator of endogenous oligodendrocyte precursor cell differentiation and remyelination.
Plasticity of photoreceptor-generating retinal progenitors revealed by prolonged retinoic acid exposure.
Stenkamp et al., Moscow, United States. In Bmc Dev Biol, 2010
The RA receptors RXR gamma and RAR alpha-b are expressed in patterns consistent with mediating the effects of RA on photoreceptors.
Association between retinoid-X receptor-gamma genetic polymorphisms and diabetic retinopathy.
Hsiao et al., Taipei, Taiwan. In Genet Mol Res, 2010
The RXR-gamma rs3818569 single nucleotide polymorphisms is associated with diabetic retinopathy development in the Taiwanese population.
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
Murray et al., Cambridge, United Kingdom. In Nat Genet, 2010
The new loci included four previously associated with body mass index (in or near FTO, SEC16B, TRA2B and TMEM18), three in or near other genes implicated in energy homeostasis (BSX, CRTC1 and MCHR2) and three in or near genes implicated in hormonal regulation (INHBA, PCSK2 and RXRG).
Retinoid x receptor gamma control of affective behaviors involves dopaminergic signaling in mice.
Krezel et al., Illkirch-Graffenstaden, France. In Neuron, 2010
The data of this study argued that control of NAc dopamine d2 receptor expression is critical for Retinoid x receptor gamma-mediated modulation of affective behaviors.
Developmental expression of retinoic acid receptors (RARs).
Dollé, France. In Nucl Recept Signal, 2008
Rxr genes also have either widespread (Rxra, Rxrb), or highly-restricted (Rxrg) expression patterns.
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