Urban et al., Baltimore, United States. In Nature, Aug 2015
To address this limitation, here we focus on intramembrane proteases containing domains known to exert regulatory functions in other contexts, and characterize a rhomboid protease that harbours calcium-binding EF-hands.
Rosenmund et al., Lausanne, Switzerland. In Nat Neurosci, Jul 2015
This high dynamic range suggests that docked and readily releasable pool (RRP) vesicles might be protected against spontaneous release while also being immediately available for ultrafast Ca(2+)-evoked release.
De Castro et al., Mar del Plata, Argentina. In Front Microbiol, 2014
The rhomboid protease RhoII is involved in the N-glycosylation of the S-layer protein with a sulfoquinovose-containing oligosaccharide while archaeosortase ArtA mediates the proteolytic processing coupled-lipid modification of this glycoprotein facilitating its attachment to the archaeal cell surface.
McQuibban et al., Toronto, Canada. In Biochim Biophys Acta, 2013
The identification of a mitochondrial-localized rhomboid protease shed light on other functions of rhomboid proteases including the maintenance of mitochondrial morphology and the regulation of apoptosis.
Albeck et al., Ramat Gan, Israel. In J Chem Theory Comput, 2012
We applied molecular dynamics and quantum mechanics calculations in order to clarify the protonation state of the catalytic residues of E. coli GlpG rhomboid protease and how it is affected by the immersion of the enzyme in the membrane.
Vasmatzis et al., Rochester, United States. In J Clin Oncol, 2008
PURPOSE: In men who are at high-risk of prostate cancer, progression and death from cancer after radical retropubic prostatectomy (RRP), limited prognostic information is provided by established prognostic features.