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Ribosomal protein S11

RPS11, ribosomal protein S11
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S17) is thought to be involved in the recognition of termination codons. This gene is co-transcribed with a small nucleolar RNA gene, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, p31, POLYMERASE, CAN, HAD
Papers on RPS11
Identification and molecular mapping of Rps11, a novel gene conferring resistance to Phytophthora sojae in soybean.
Ma et al., West Lafayette, United States. In Theor Appl Genet, Jan 2016
KEY MESSAGE: Rps11 confers excellent resistance to predominant Phytophthora sojae isolates capable of defeating major Rps genes deployed into soybean production, representing a novel source of resistance for soybean cultivar enhancement.
Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.
Zhang et al., Philadelphia, United States. In Cell Cycle, 2014
This includes several translation initiation factors (eIF2C2, eIF2B4, eIF3I, eIF3L, eIF4A1) and elongation factors (eEF1G, eEF1A) as well as 40S (RPS4X, RPS7, RPS11 and RPS20) and 60S ribosomal subunits (RPL10, RPL11, RPL18 and RPL35a).
Ribosomal Proteins RPS11 and RPS20, Two Stress-Response Markers of Glioblastoma Stem Cells, Are Novel Predictors of Poor Prognosis in Glioblastoma Patients.
Tso et al., Los Angeles, United States. In Plos One, 2014
Ribosomal protein S11 (RPS11), RPS20, individually and together, consistently predicted poor survival of newly diagnosed primary GBM tumors when overexpressed at the RNA or protein level [RPS11: Hazard Ratio (HR) = 11.5, p<0.001;
Meta-analysis of differentially expressed genes in ankylosing spondylitis.
Song et al., Seoul, South Korea. In Genet Mol Res, 2014
The downregulated gene with the largest ES (1.2299, P = 0.040075) was mitochondrial ribosomal protein S11 (MRPS11).
Differential Genes Expression between Fertile and Infertile Spermatozoa Revealed by Transcriptome Analysis.
Rajender et al., Lucknow, India. In Plos One, 2014
Analysis of these transcripts showed that some transcripts [ribosomal proteins (RPS25, RPS11, RPS13, RPL30, RPL34, RPL27, RPS5), HINT1, HSP90AB1, SRSF9, EIF4G2, ILF2] were up-regulated in the normozoospermic group, but down-regulated in the asthenozoospermic group in comparison to the control group.
Identification of reference genes for qRT-PCR in human lung squamous-cell carcinoma by RNA-Seq.
Wang et al., Shanghai, China. In Acta Biochim Biophys Sin (shanghai), 2014
In contrast, 1 of the 15 common reference genes (ACTB) and the 5 additional candidate reference genes (EEF1A1, FAU, RPS9, RPS11, and RPS14) were stably and constitutively expressed at high levels in all the samples tested.
Selection and evaluation of potential reference genes for gene expression analysis in the brown planthopper, Nilaparvata lugens (Hemiptera: Delphacidae) using reverse-transcription quantitative PCR.
Li et al., Wuhan, China. In Plos One, 2013
In this paper, we presented a systematic exploration of eight candidate reference genes in N. lugens, namely, actin 1 (ACT), muscle actin (MACT), ribosomal protein S11 (RPS11), ribosomal protein S15e (RPS15), alpha 2-tubulin (TUB), elongation factor 1 delta (EF), 18S ribosomal RNA (18S), and arginine kinase (AK) and used four alternative methods (BestKeeper, geNorm, NormFinder, and the delta Ct method) to evaluate the suitability of these genes as endogenous controls.
MiR-125b, miR-100 and miR-99a co-regulate vincristine resistance in childhood acute lymphoblastic leukemia.
den Boer et al., Rotterdam, Netherlands. In Leuk Res, 2013
Co-expression of these miRNAs resulted in downregulation of DNTT, NUCKS1, MALAT1, SNRPE, PNO1, SET, KIF5B, PRPS2, RPS11, RPL38 and RPL23A (fold-change 1.3-1.9,
Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
Morris et al., Chapel Hill, United States. In Am J Hum Genet, 2012
Through transethnic meta-analysis of European-ancestry and Japanese genome-wide association studies, we identified six loci at genome-wide significance (p < 5 × 10(-8)) for serum albumin (HPN-SCN1B, GCKR-FNDC4, SERPINF2-WDR81, TNFRSF11A-ZCCHC2, FRMD5-WDR76, and RPS11-FCGRT, in up to 53,190 European-ancestry and 9,380 Japanese individuals) and three loci for total protein (TNFRS13B, 6q21.3, and ELL2, in up to 25,539 European-ancestry and 10,168 Japanese individuals).
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
Cho et al., South Korea. In Nat Genet, 2011
(in C12orf51) for high-density lipoprotein cholesterol, 2p21 (near SIX2-SIX3) for fasting plasma glucose, 19q13.33 (in RPS11) and 6q22.33 (in RSPO3) for renal traits, and 12q24.11
Giant panda ribosomal protein S14: cDNA, genomic sequence cloning, sequence analysis, and overexpression.
Zhang et al., Nanchong, China. In Genet Mol Res, 2009
Topology prediction shows that there are two N-glycosylation sites, three protein kinase C phosphorylation sites, two casein kinase II phosphorylation sites, four N-myristoylation sites, two amidation sites, and one ribosomal protein S11 signature in the RPS14 protein of the giant panda.
Expression profiling of fecal colonocytes for RNA-based screening of colorectal cancer.
Sasaki et al., Tokyo, Japan. In Int J Oncol, 2007
Six genes (SEPP1, RPL27A, ATP1B1, EEF1A1, SFN, and RPS11) selected randomly from 85 cancer patient-derived colonocyte-specific genes were evaluated.
ZNF143 activates gene expression in response to DNA damage and binds to cisplatin-modified DNA.
Kohno et al., Fukuoka, Japan. In Int J Cancer, 2004
We have identified a cisplatin-inducible gene, the mitochondrial ribosomal protein S11 (MRP S11) gene, by means of mRNA differential display.
Interactions of yeast ribosomal protein rpS14 with RNA.
Woolford et al., Pittsburgh, United States. In J Mol Biol, 2003
We used the three-dimensional structure of Thermus thermophilus ribosomal protein S11, a bacterial homologue of rpS14, as a guide to identify conserved, surface-exposed amino acid residues that are likely to contact RNA.
The ribosomal protein QM is expressed differentially during vertebrate endochondral bone development.
Wallis et al., Manchester, United Kingdom. In J Bone Miner Res, 2000
In contrast, no detectable difference in the expression of mRNA for the ribosomal protein S11 was detected.
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