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Ribosomal protein L34

rpL34, ribosomal protein L34, leukemia-associated protein SET
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L34E family of ribosomal proteins. It is located in the cytoplasm. This gene originally was thought to be located at 17q21, but it has been mapped to 4q. Transcript variants derived from alternative splicing, alternative transcription initiation sites, and/or alternative polyadenylation exist; these variants encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, POLYMERASE, PP2A, SET, CAN
Papers on rpL34
RNAi-mediated RPL34 knockdown suppresses the growth of human gastric cancer cells.
Rui et al., Wuhu, China. In Oncol Rep, Nov 2015
To examine the role of ribosomal protein L34 (RPL34) in cancer transformation, we assessed its expression in gastric cancer cell lines and found it highly expressed.
Defect in the formation of 70S ribosomes caused by lack of ribosomal protein L34 can be suppressed by magnesium.
Ishizuka et al., Tokyo, Japan. In J Bacteriol, 2014
To elucidate the biological functions of the ribosomal protein L34, which is encoded by the rpmH gene, the rpmH deletion mutant of Bacillus subtilis and two suppressor mutants were characterized.
Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection.
Iqbal et al., New York City, United States. In Acta Neuropathol, 2014
The activity of protein phosphatase-2A (PP2A), which regulates the phosphorylation of tau and neurofilaments, is negatively regulated by the myeloid leukemia-associated protein SET, also known as inhibitor-2 of PP2A, I2(PP2A).
Identification of a functional splice variant of 14-3-3E1 in rainbow trout.
Yao et al., Morgantown, United States. In Mar Biotechnol (ny), 2010
Analysis by yeast two-hybrid system demonstrated that 14-3-3E1Delta17 interacts with a number of proteins including ATP synthase, ankyrin repeat domain 13b, cytochrome c subunit VIa, cytochrome c subunit VIb, 60S ribosomal protein L34, solute carrier family 17 member 6 (SLC17A6), troponin I, and an unknown protein.
Dystroglycan and mitochondrial ribosomal protein L34 regulate differentiation in the Drosophila eye.
Carbonetto et al., Montréal, Canada. In Plos One, 2009
Mutations that diminish the function of the extracellular matrix receptor Dystroglycan (DG) result in muscular dystrophies, with associated neuronal migration defects in the brain and mental retardation e.g.
Thermostable RNase P RNAs lacking P18 identified in the Aquificales.
Willkomm et al., Marburg an der Lahn, Germany. In Rna, 2006
As in most bacteria, the rnpA genes of S. azorense and P. marina are preceded by the rpmH gene coding for ribosomal protein L34.
Proteome analysis of NIH3T3 cells transformed by activated Galpha12: regulation of leukemia-associated protein SET.
Dhanasekaran et al., Philadelphia, United States. In J Proteome Res, 2004
Galpha(12), the alpha-subunit of the G12 family of heterotrimeric G proteins is involved in the regulation of cell proliferation and neoplastic transformation.
Sequencing and characterization of the Xenopus laevis ribosomal protein L34 cDNA.
Vaccaro, Napoli, Italy. In Gene, 2003
In this paper, a cDNA homologous to the mammalian ribosomal protein (r-protein) L34 was isolated from a Xenopus laevis oocytes library and named XL34.
Genes within genes within bacteria.
Brown et al., Raleigh, United States. In Trends Biochem Sci, 2003
Recently, an unusual gene structure has been described in species of the genus Thermus, in which the rpmH (ribosomal protein L34) coding sequence was found to be entirely overlapped by the unusually large rnpA (RNase P protein subunit) sequence.
Ribosomal protein P0 from Aedes albopictus mosquito cells: cDNA cloning and analysis of expression.
Fallon et al., Saint Paul, United States. In Genetica, 2003
When cells were exposed to various stresses, expression of P0 appeared to differ from that of rpL34.
An unusual mechanism of bacterial gene expression revealed for the RNase P protein of Thermus strains.
Hartmann et al., Lübeck, Germany. In Proc Natl Acad Sci U S A, 2003
The RNase P protein gene (rnpA) completely overlaps the rpmH gene (encoding ribosomal protein L34) out of frame in the thermophilic bacterium Thermus thermophilus.
A ribosome-free extract from cultured cells improves recovery of polysomes from the mosquito fat body: analysis of vitellogenin and ribosomal protein rpL34 gene expression.
Fallon et al., Saint Paul, United States. In J Insect Physiol, 2002
We have examined the association of ribosomal protein rpL34 mRNA with polysomes in Aedes albopictus C7-10 cells in culture using a simple, two-step sucrose gradient.
Identification and characterization of SEB, a novel protein that binds to the acute undifferentiated leukemia-associated protein SET.
Adachi et al., Uji, Japan. In Eur J Biochem, 2001
SET, the translocation breakpoint-encoded protein in acute undifferentiated leukemia (AUL), is a 39-kDa nuclear phosphoprotein and has an inhibitory activity for protein phosphatase 2A (PP2A).
Molecular cloning and complete cDNA sequences of the ribosomal proteins rpl34 and rpl44 from Aedes triseriatus mosquitoes.
Beaty et al., Fort Collins, United States. In Dna Seq, 1999
We present the complete cDNA and deduced amino acid sequences of the 60S ribosomal subunit proteins, rpL34 and rpL44, from Aedes triseriatus mosquitoes.
The primary structure of a gene encoding yeast ribosomal protein L34.
Planta et al., Amsterdam, Netherlands. In Curr Genet, 1984
Sequence analysis revealed that a gene coding for yeast ribosomal protein L34 comprises an amino acid coding region of 339 nucleotides which is interrupted by an intron after the 19th codon.
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