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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

RPL3 Rpl3p

RPL3, TCM1, ribosomal protein L3, l-4, mak8
Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on RPL3
Autoregulatory circuit of human rpL3 expression requires hnRNP H1, NPM and KHSRP.
Russo et al., Napoli, Italy. In Nucleic Acids Res, 2011
NPM and KHSRP are two newly identified proteins involved in the regulation of rpL3 gene expression via alternative pre-mRNA splicing.
A novel 3-methylhistidine modification of yeast ribosomal protein Rpl3 is dependent upon the YIL110W methyltransferase.
Clarke et al., Los Angeles, United States. In J Biol Chem, 2010
3-methylhistidine modification of Rpl3 is dependent upon the YIL110W methyltransferase.
hnRNP H1 and intronic G runs in the splicing control of the human rpL3 gene.
Russo et al., Napoli, Italy. In Biochim Biophys Acta, 2010
working model in which rpL3 recruits hnRNP H1 and, through cooperation with other splicing factors, promotes selection of the alternative splice site
Functional analysis of Saccharomyces cerevisiae ribosomal protein Rpl3p in ribosome synthesis.
de la Cruz et al., Sevilla, Spain. In Nucleic Acids Res, 2006
Upon depletion of Rpl3p, early assembly of 60S ribosomal subunits is aborted and subsequent steps during their maturation and export prevented.
Identification of Saccharomyces cerevisiae ribosomal protein L3 as a target of curvularol, a G1-specific inhibitor of mammalian cells.
Miyakawa et al., Hiroshima, Japan. In Biosci Biotechnol Biochem, 2006
A mutant gene responsible for curvularol resistance was identified as an allele of the RPL3 gene encoding the ribosomal protein L3.
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